Concomitant active tuberculosis prolongs survival in non-small cell lung cancer: A study in a tuberculosis-endemic country

Chih Hsi Kuo, Chun Yu Lo, Fu Tsai Chung, Kang Yun Lee, Shu Min Lin, Chun Hua Wang, Chih Chen Heh, Hao Cheng Chen, Han Pin Kuo

研究成果: 雜誌貢獻文章同行評審

18 引文 斯高帕斯(Scopus)

摘要

Background: Adjuvant tumor cell vaccine with chemotherapy against non-small cell lung cancer (NSCLC) shows limited clinical response. Whether it provokes effective cellular immunity in tumor microenvironment is questionable. Concomitant active tuberculosis in NSCLC (TBLC) resembles locoregional immunotherapy of tumor cell vaccine; thus, maximally enriches effective anti-tumor immunity. This study compares the survival and immunological cell profile in TBLC over NSCLC alone. Methods: Retrospective review of NSCLC patients within 1-year-period of 2007 and follow-up till 2010. Results: A total 276 NSCLC patients were included. The median survival of TBLC is longer than those of NSCLC alone (11.6 vs. 8.8 month, p
原文英語
文章編號e33226
期刊PLoS One
7
發行號3
DOIs
出版狀態已發佈 - 三月 16 2012
對外發佈Yes

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

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