Complete sequences of two plasmids in a blandm-1-positive klebsiella oxytoca isolate from taiwan

Tzu Wen Huang, Jann Tay Wang, Tsai Ling Lauderdale, Tsai Lien Liao, Jui Fen Lai, Mei Chen Tan, Ann Chi Lin, Ying Tsong Chen, Shih Feng Tsai, Shan Chwen Chang

研究成果: 雜誌貢獻文章同行評審

44 引文 斯高帕斯(Scopus)

摘要

Genetic determinants of a blaNDM-1-positive, multidrug-resistant bacterial isolate that caused active infection was investigated by DNA sequencing. Two plasmids, pKOX-NDM1 and pKOX-R1, were identified for the Klebsiella oxytoca strain E718. Sequence annotation revealed a blaNDM-1 gene in pKOX-NDM1 and two extended-spectrum-lactamase producers (blaCTX-M-3 and blaSHV-12) and a wide array of resistance genes in pKOX-R1. These findings highlight the difficulty in treating multidrugresistant bacterial infections and the potential danger of emerging resistant enterobacteria.

原文英語
頁(從 - 到)4072-4076
頁數5
期刊Antimicrobial Agents and Chemotherapy
57
發行號8
DOIs
出版狀態已發佈 - 八月 2013
對外發佈

ASJC Scopus subject areas

  • 藥學(醫學)
  • 藥理
  • 傳染性疾病

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