Comparisons of risk factors and visual field changes between juvenile-onset and late-onset primary open-angle glaucoma

Yu Chieh Ko, Catherine Jui Ling Liu, Joe Ching Kuang Chou, Mei Ru Chen, Wen-Ming Hsu, Jorn Hon Liu

研究成果: 雜誌貢獻文章

13 引文 斯高帕斯(Scopus)

摘要

Purpose: To identify the differences in risk factors and visual field (VF) changes between juvenile primary open-angle glaucoma (JOAG) and late-onset chronic open-angle glaucoma (COAG). Methods: The demographic and presenting clinical data of 27 JOAG and 30 COAG patients were retrospectively reviewed. Comparisons between the two groups were performed using Mann-Whitney U test, Wilcoxon signed-rank test, and Fisher's exact test. Results: A family history of glaucoma (37%) and a history of steroid usage (14.8%) were identified in JOAG patients only. The JOAG patients had a longer axial length (p < 0.001) and more often a myopic refractive state (p < 0.001) than the COAG patients. Patients with COAG showed a deeper (p = 0.016) and a more extensive (p = 0.008) defect in the superior than in the inferior hemifield, as well as a deeper (p = 0.016) and a more extensive (p = 0.001) defect in the superior than in the inferior arcuate area, while JOAG patients showed symmetric VF defects between the superior and inferior hemifields. Purely diffuse VF depression is more common in JOAG than in COAG patients (p = 0.03). Conclusions: JOAG patients demonstrated more axial myopic changes than patients with COAG as well as a pattern of superior-inferior symmetric VF defects. Axial myopia may play a critical role in the pathogenesis of JOAG.

原文英語
頁(從 - 到)27-32
頁數6
期刊Ophthalmologica
216
發行號1
DOIs
出版狀態已發佈 - 四月 6 2002
對外發佈Yes

ASJC Scopus subject areas

  • Ophthalmology

指紋 深入研究「Comparisons of risk factors and visual field changes between juvenile-onset and late-onset primary open-angle glaucoma」主題。共同形成了獨特的指紋。

  • 引用此