Comparison of human and chimpanzee ξ1 blobin genes

Cary Willard, Elsie Wong, John F. Hess, Che Kun James Shen, Barbara Chapman, Allan C. Wilson, Carl W. Schmid

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13 引文 斯高帕斯(Scopus)


The DNA base sequences of the entire chimpanzee ξ1 globin gene and an additional 1 kb of DNA flanking both the human and chimpanzee genes have been determined. Whereas the human ξ1 gene contains a termination codon in the sixth position, the chimpanzee gene appears to be functional. This finding confirms Proudfoot et al.'s suggestion that the human ξ1 gene was recently inactivated. Like the corresponding human ξ1 and ξ2 genes, the first and second introns of the chimpanzee ξ1 gene are occupied largely by tandem repeats of short oligonucleotides. These tandem repeats have undergone several rearrangements since the divergence of the human and chimpanzee ξ1 genes.

頁(從 - 到)309-315
期刊Journal of Molecular Evolution
出版狀態已發佈 - 十二月 1985

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Molecular Biology
  • Genetics

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    Willard, C., Wong, E., Hess, J. F., James Shen, C. K., Chapman, B., Wilson, A. C., & Schmid, C. W. (1985). Comparison of human and chimpanzee ξ1 blobin genes. Journal of Molecular Evolution, 22(4), 309-315.