Comparison of gram-negative and gram-positive hematogenous pyogenic spondylodiscitis: Clinical characteristics and outcomes of treatment

Ching Yu Lee, Meng Huang Wu, Chin Chang Cheng, Tsung-Jen Huang, Yu Tsung Huang, Chien Yin Lee, Jou Chen Huang, Yen Yao Li

研究成果: 雜誌貢獻文章同行評審

5 引文 斯高帕斯(Scopus)

摘要

Background: To the best of our knowledge, no study has compared gram-negative bacillary hematogenous pyogenic spondylodiscitis (GNB-HPS) with gram-positive coccal hematogenous pyogenic spondylodiscitis (GPC-HPS) regarding their clinical characteristics and outcomes. Methods: From January 2003 to January 2013, 54 patients who underwent combined antibiotic and surgical therapy in the treatment of hematogenous pyogenic spondylodiscitis were included. Results: Compared with 37 GPC-HPS patients, the 17 GNB-HPS patients were more often found to be older individuals, a history of cancer, and a previous history of symptomatic urinary tract infection. They also had a less incidence of epidural abscess formation compared with GPC-HPS patients from findings on magnetic resonance imaging (MRI). Constitutional symptoms were the primary reasons for initial physician visits in GNB-HPS patients whereas pain in the affected spinal region was the most common manifestation in GPC-HPS patients at initial visit. The clinical outcomes of GNB-HPS patients under combined surgical and antibiotic treatment were not different from those of GPC-HPS patients. In multivariate analysis, independent predicting risk factors for GNB-HPS included a malignant history and constitutional symptoms and that for GPC-HPS was epidural abscess. Conclusions: The clinical manifestations and MRI presentations of GNB-HPS were distinguishable from those of GPC-HPS.
原文英語
文章編號735
期刊BMC Infectious Diseases
16
發行號1
DOIs
出版狀態已發佈 - 十二月 6 2016

ASJC Scopus subject areas

  • Infectious Diseases

指紋 深入研究「Comparison of gram-negative and gram-positive hematogenous pyogenic spondylodiscitis: Clinical characteristics and outcomes of treatment」主題。共同形成了獨特的指紋。

引用此