Comparison of Charlson comorbidity index and Kaplan-Feinstein index in patients with stage I lung cancer after surgical resection

Chien Ying Wang, Yu Sen Lin, Ching Tzao, Hui Chen Lee, Min Hsiung Huang, Wen Hu Hsu, Han Shui Hsu

研究成果: 雜誌貢獻文章同行評審

50 引文 斯高帕斯(Scopus)

摘要

Objective: We sought to determine whether Charlson comorbidity index (CCI) or Kaplan-Feinstein index (KFI) is a better predictor of prognosis in patients with stage I NSCLC after surgical resection. Methods: A retrospective study of medical records of 426 patients with stage I lung cancer having complete surgical resection from 1995 to 2000 was performed. Data collected included age, gender, smoking history, resection type, pleural invasion status, and tumor type and size. Comorbidity score was determined using Charlson comorbidity index and Kaplan-Feinstein index. Both univariate and multivariate analyses were used to evaluate prognostic factors. Results: Three hundred and twenty-eight male (76.99%) and 98 female (23.01%) patients had a mean age of 67.07 years (range 19-88 years). Median duration of follow-up was 60.32 months. Total follow-up rate was 95.1%. Distribution of CCI score was: 0, 236 (55.40%); 1, 112 (26.29%); ≥2, 78 (18.31%). Overall KFI score was: none, 247 (57.98%); mild, 126 (29.58%); moderate, 43 (10.09%); and severe, 10 (2.35%). In univariate analyses, patients aged ≥65 years, male, smokers, CCI score ≥2, extensive resection and pathological stage IB cancer had poorer 5-year survival. In multivariate logistic regression analysis, age ≥65 years, pneumonectomy, CCI score ≥2, and stage IB cancer were independent prognostic factors for poorer 5-year survival. Conclusions: Patients with CCI ≥2 had higher perioperative mortality and death from non-cancer causes after surgery compared to patients with CCI

原文英語
頁(從 - 到)877-881
頁數5
期刊European Journal of Cardio-thoracic Surgery
32
發行號6
DOIs
出版狀態已發佈 - 十二月 2007
對外發佈Yes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

指紋 深入研究「Comparison of Charlson comorbidity index and Kaplan-Feinstein index in patients with stage I lung cancer after surgical resection」主題。共同形成了獨特的指紋。

引用此