Comparison of Carotid Ultrasound Indices and the Triglyceride Glucose Index in Hypertensive and Normotensive Community-Dwelling Individuals

A Case Control Study for Evaluating Atherosclerosis

Javad Alizargar, Chyi Huey Bai

研究成果: 雜誌貢獻文章

1 引文 (Scopus)

摘要

Background and objectives: Hypertension (HTN) is an important risk factor for cardiovascular diseases. High blood pressure is a major cause of atherosclerosis which leads to myocardial infarction and stroke. Insulin resistance (IR) is correlated with HTN and atherosclerosis. To determine differences between the effects of HTN on the intima media thicknesses (IMTs) of the internal (ICA), external (ECA), and common carotid arteries (CCA), and evaluate the carotid plaque presence between hypertensive and normotensive individuals, a case-control study was designed among community-dwelling individuals. The relationship between the triglyceride glucose (TyG) index and atherosclerosis was also investigated in this study. Materials and Methods: Data from 77 hypertensive and 199 normotensive individuals were analyzed in this study. Results: The IMTs of the CCA, ICA, and ECA, and the TyG index were all higher in hypertensive individuals compared to the control group (all p < 0.05). After controlling for age, sex, the body-mass index, and TyG index, HTN was an independent predictor of a high CCA IMT (odds ratio (OR) = 2.48; 95% confidence interval (CI) = 1.24⁻4.93) and presence of plaque (OR = 2.36; CI = 1.15⁻4.85) in the carotid artery. Conclusions: HTN was an independent risk of carotid IMT thickening and atherosclerosis. TyG index could only predict the CCA IMT independent of other risk factors (OR = 2.09; CI = 1.07⁻4.09).
原文英語
期刊Medicina (Kaunas, Lithuania)
54
發行號5
DOIs
出版狀態已發佈 - 十月 11 2018

指紋

Independent Living
Case-Control Studies
Atherosclerosis
Triglycerides
Common Carotid Artery
Hypertension
Glucose
Carotid Intima-Media Thickness
Odds Ratio
Confidence Intervals
External Carotid Artery
Carotid Arteries
Insulin Resistance
Body Mass Index
Cardiovascular Diseases
Stroke
Myocardial Infarction
Control Groups

Keywords

  • atherosclerosis
  • carotid artery
  • carotid intima media thickness
  • hypertension
  • insulin resistance
  • risk factor
  • triglyceride glucose index

ASJC Scopus subject areas

  • Medicine(all)

引用此文

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title = "Comparison of Carotid Ultrasound Indices and the Triglyceride Glucose Index in Hypertensive and Normotensive Community-Dwelling Individuals: A Case Control Study for Evaluating Atherosclerosis",
abstract = "Background and objectives: Hypertension (HTN) is an important risk factor for cardiovascular diseases. High blood pressure is a major cause of atherosclerosis which leads to myocardial infarction and stroke. Insulin resistance (IR) is correlated with HTN and atherosclerosis. To determine differences between the effects of HTN on the intima media thicknesses (IMTs) of the internal (ICA), external (ECA), and common carotid arteries (CCA), and evaluate the carotid plaque presence between hypertensive and normotensive individuals, a case-control study was designed among community-dwelling individuals. The relationship between the triglyceride glucose (TyG) index and atherosclerosis was also investigated in this study. Materials and Methods: Data from 77 hypertensive and 199 normotensive individuals were analyzed in this study. Results: The IMTs of the CCA, ICA, and ECA, and the TyG index were all higher in hypertensive individuals compared to the control group (all p < 0.05). After controlling for age, sex, the body-mass index, and TyG index, HTN was an independent predictor of a high CCA IMT (odds ratio (OR) = 2.48; 95{\%} confidence interval (CI) = 1.24⁻4.93) and presence of plaque (OR = 2.36; CI = 1.15⁻4.85) in the carotid artery. Conclusions: HTN was an independent risk of carotid IMT thickening and atherosclerosis. TyG index could only predict the CCA IMT independent of other risk factors (OR = 2.09; CI = 1.07⁻4.09).",
keywords = "atherosclerosis, carotid artery, carotid intima media thickness, hypertension, insulin resistance, risk factor, triglyceride glucose index, atherosclerosis, carotid artery, carotid intima media thickness, hypertension, insulin resistance, risk factor, triglyceride glucose index",
author = "Javad Alizargar and Bai, {Chyi Huey}",
year = "2018",
month = "10",
day = "11",
doi = "10.3390/medicina54050071",
language = "English",
volume = "54",
journal = "Medicina",
issn = "1010-660X",
publisher = "Kauno Medicinos Universitetas",
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}

TY - JOUR

T1 - Comparison of Carotid Ultrasound Indices and the Triglyceride Glucose Index in Hypertensive and Normotensive Community-Dwelling Individuals

T2 - A Case Control Study for Evaluating Atherosclerosis

AU - Alizargar, Javad

AU - Bai, Chyi Huey

PY - 2018/10/11

Y1 - 2018/10/11

N2 - Background and objectives: Hypertension (HTN) is an important risk factor for cardiovascular diseases. High blood pressure is a major cause of atherosclerosis which leads to myocardial infarction and stroke. Insulin resistance (IR) is correlated with HTN and atherosclerosis. To determine differences between the effects of HTN on the intima media thicknesses (IMTs) of the internal (ICA), external (ECA), and common carotid arteries (CCA), and evaluate the carotid plaque presence between hypertensive and normotensive individuals, a case-control study was designed among community-dwelling individuals. The relationship between the triglyceride glucose (TyG) index and atherosclerosis was also investigated in this study. Materials and Methods: Data from 77 hypertensive and 199 normotensive individuals were analyzed in this study. Results: The IMTs of the CCA, ICA, and ECA, and the TyG index were all higher in hypertensive individuals compared to the control group (all p < 0.05). After controlling for age, sex, the body-mass index, and TyG index, HTN was an independent predictor of a high CCA IMT (odds ratio (OR) = 2.48; 95% confidence interval (CI) = 1.24⁻4.93) and presence of plaque (OR = 2.36; CI = 1.15⁻4.85) in the carotid artery. Conclusions: HTN was an independent risk of carotid IMT thickening and atherosclerosis. TyG index could only predict the CCA IMT independent of other risk factors (OR = 2.09; CI = 1.07⁻4.09).

AB - Background and objectives: Hypertension (HTN) is an important risk factor for cardiovascular diseases. High blood pressure is a major cause of atherosclerosis which leads to myocardial infarction and stroke. Insulin resistance (IR) is correlated with HTN and atherosclerosis. To determine differences between the effects of HTN on the intima media thicknesses (IMTs) of the internal (ICA), external (ECA), and common carotid arteries (CCA), and evaluate the carotid plaque presence between hypertensive and normotensive individuals, a case-control study was designed among community-dwelling individuals. The relationship between the triglyceride glucose (TyG) index and atherosclerosis was also investigated in this study. Materials and Methods: Data from 77 hypertensive and 199 normotensive individuals were analyzed in this study. Results: The IMTs of the CCA, ICA, and ECA, and the TyG index were all higher in hypertensive individuals compared to the control group (all p < 0.05). After controlling for age, sex, the body-mass index, and TyG index, HTN was an independent predictor of a high CCA IMT (odds ratio (OR) = 2.48; 95% confidence interval (CI) = 1.24⁻4.93) and presence of plaque (OR = 2.36; CI = 1.15⁻4.85) in the carotid artery. Conclusions: HTN was an independent risk of carotid IMT thickening and atherosclerosis. TyG index could only predict the CCA IMT independent of other risk factors (OR = 2.09; CI = 1.07⁻4.09).

KW - atherosclerosis

KW - carotid artery

KW - carotid intima media thickness

KW - hypertension

KW - insulin resistance

KW - risk factor

KW - triglyceride glucose index

KW - atherosclerosis

KW - carotid artery

KW - carotid intima media thickness

KW - hypertension

KW - insulin resistance

KW - risk factor

KW - triglyceride glucose index

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