Comorbidities of dry eye disease: A nationwide population-based study

Tsung-Jen Wang, I. Jong Wang, Chao Chien Hu, Herng-Ching Lin

研究成果: 雜誌貢獻文章

53 引文 斯高帕斯(Scopus)

摘要

Purpose: To investigate the comorbidities of dry eye disease in a nationwide population-based data in Taiwan. Methods: This study features a study group and a comparison group. The study group comprised 12 007 patients who sought ambulatory care for treatment of dry eye in 2005 and 2006. In total, 36 021 randomly selected patients were in the comparison group. Conditional logistic regression analyses conditioned on gender, age, monthly income and level of urbanization of the community in which the patient resided were conducted to calculate the odds ratio (OR) for each of 33 comorbidities among patients with and without dry eye disease. Results: The regression analyses revealed that compared to patients without dry eye disease, patients with dry eye disease were more likely to have comorbidities of ischaemic heart disease (OR = 1.36), hyperlipidaemia (OR = 1.68), cardiac arrhythmias (OR = 1.55), peripheral vascular disorders (OR = 1.57), stroke (OR = 1.31), migraines (OR = 1.76), myasthenia gravis (OR = 2.85), RA (OR = 2.86), systemic lupus erythematosus (OR = 3.98), asthma (OR = 1.25), pulmonary circulation disorders (OR = 1.37), diabetes with complications (OR = 1.31), hypothyroidism (OR = 1.94), liver diseases (OR = 1.71), peptic ulcers (OR = 1.76), hepatitis B (OR = 1.64), deficiency anaemias (OR = 1.31), depression (OR = 2.11), psychoses (OR = 1.87) and solid tumours without metastasis (OR = 1.41). Conclusions: This study demonstrates significantly higher prevalence of medical comorbidities in patients with dry eye disease in Taiwan.
原文英語
頁(從 - 到)663-668
頁數6
期刊Acta Ophthalmologica
90
發行號7
DOIs
出版狀態已發佈 - 十一月 2012

ASJC Scopus subject areas

  • Ophthalmology

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