Combination of molecular assay and clinical evaluation for early confirmation of tuberculosis cases

Hui Z. Tu, Yao Shen Chen, Y. E. Lin, M. R. Tseng, Tsi S. Huang, Hung Chin Tsai, Yung-Ching Liu

研究成果: 雜誌貢獻文章同行評審

2 引文 斯高帕斯(Scopus)

摘要

The cost-effectiveness of the ProbeTec ET Direct TB assay (DTB) was compared with that of culture for detection of Mycobacterium tuberculosis complex in 361 acid-fast stain-positive respiratory specimens. The overall sensitivity, specificity, positive predictive value and negative predictive value of DTB were 97.7%, 86.6%, 87.2% and 97.6%, respectively. When clinical evaluation was added to DTB, the specificity and positive predictive value of DTB increased to 94.7% and 95.4%, respectively. Treatment costs of $133521 would have been saved in this cohort if DTB, instead of culture results, had been used to eliminate 'false-positive' smear results.
原文英語
頁(從 - 到)712-714
頁數3
期刊Clinical Microbiology and Infection
17
發行號5
DOIs
出版狀態已發佈 - 五月 2011

ASJC Scopus subject areas

  • 微生物學(醫學)
  • 傳染性疾病

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