Combination of baclofen and antimuscarinics to reduce voiding difficulty in treating women with overactive bladders

H. Y. Chin, K. C. Lin, C. H. Chiang, C. J. Wang

研究成果: 雜誌貢獻文章同行評審

6 引文 斯高帕斯(Scopus)

摘要

Purposte of study: To evaluate the efficacy of baclofen in combination with antimuscarinics to treat women with an overactive bladder (OAB) with abnormal voiding patterns. Methods: An action research and chart review was conducted in 245 OAB women. Women were prescribed tolterodine or oxybutynin with or without baclofen after urodynamics. The complaint of voiding difficulty was followed up one week later. Results: There was a significant difference in the occurrence of voiding difficulty after antimuscarinic administration in OAB women with abnormal voiding patterns compared with normal patterns (18% vs 4.9%, respectively; p = 0.013). The clinical difference of voiding difficulty after treating with antimuscarinics between both voiding patterns disappeared after adding baclofen (abnormal voiding pattern vs normal pattern; 11.1% vs 5.6%, respectively; p = 1.000). Conclusion: Combined use of baclofen and antimuscarinic agents could reduce voiding difficulty in treating women with overactive bladders with abnormal voiding patterns.
原文英語
頁(從 - 到)171-174
頁數4
期刊Clinical and Experimental Obstetrics and Gynecology
39
發行號2
出版狀態已發佈 - 七月 13 2012
對外發佈Yes

Keywords

  • Antimuscarinics
  • Baclofen
  • Overactive bladder
  • Urodynamics
  • Voiding pattern

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynaecology

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