Cognitive dysfunction and medical morbidity in elderly outpatients with bipolar disorder

Shang Ying Tsai, Chian Jue Kuo, Kuo Hsuan Chung, Yi Lin Huang, Hsin Chien Lee, Chiao Chicy Chen

研究成果: 雜誌貢獻文章

34 引文 斯高帕斯(Scopus)

摘要

OBJECTIVE: The authors investigated the differences in cognitive function, medical burden, and sociodemographic characteristics between elderly community-dwelling bipolar patients and age-matched and education-matched normal individuals. DESIGN: Case-control study. SETTING: Taipei Medical University Hospital, with 75 psychiatric beds, and Taipei City Psychiatric Center-a 612-bed psychiatric teaching hospital providing comprehensive psychiatric services. PARTICIPANTS: Eighty-two euthymic outpatients with bipolar I disorder aged older than 60 years received assessment for research purpose, 59 of whom were matched with one normal control for age and years of education. MEASUREMENTS: All subjects had measurements of cognitive function (Clock-drawing test and Mini-Mental State Examination [MMSE]). Medical morbidity and health condition were according to the medical records, results of free annual elderly health examination, and physical examination on research interviewing. RESULTS: Elderly bipolar patients were found to be more likely than the comparison group to have diabetes mellitus (27.1%), atopic diseases (20.3%), abnormal education-adjusted MMSE scores (32.2%), smoking habit (23.7%), and unfavorable social functioning (22%). Despite having noticeably higher heart rates, the bipolar patients' mean systolic blood pressure and prevalence of hypertension (44.1%) were significantly lower than those of the comparison group. CONCLUSIONS: Although community-dwelling elderly patients with bipolar disorder seem to be characterized by a greater likelihood of developing cognitive dysfunction and concurrent diabetes mellitus, there is no apparent increase in the morbidity of circulatory diseases, particularly less hypertension among those without previous dementia.
原文英語
頁(從 - 到)1004-1011
頁數8
期刊American Journal of Geriatric Psychiatry
17
發行號12
DOIs
出版狀態已發佈 - 十二月 2009

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Geriatrics and Gerontology

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