Coexistence of localized Langerhans cell histiocytosis and cutaneous Rosai-Dorfman disease

K. H. Wang, C. J. Cheng, Jun-Hung Hu, W. R. Lee

研究成果: 雜誌貢獻文章

42 引文 斯高帕斯(Scopus)

摘要

Rosai-Dorfman disease (RDD; sinus histiocytosis with massive lymphadenopathy) and Langerhans cell histiocytosis (LCH) are two different yet pathogenetically related histiocytic disorders. While systemic and localized forms have been identified in both diseases, each has its own characteristic histological, immunohistochemical and ultrastructural profile. Rarely, either RDD or LCH can also occur in the context of certain malignant neoplasms. However, the coexistence of RDD and LCH has never been described. We report a case of cutaneous RDD in which a focus of LCH was found. Clinical and laboratory examinations revealed no evidence of extracutaneous involvement of RDD or LCH. We believe that this is the first report of such a coexistence, and the possible pathogenesis is discussed.
原文英語
頁(從 - 到)770-774
頁數5
期刊British Journal of Dermatology
147
發行號4
DOIs
出版狀態已發佈 - 2002

ASJC Scopus subject areas

  • Dermatology

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