Cobalt Chloride Induces Macrophage Foam Cell Formation: A Chemical Hypoxia Model for Anti-Atherosclerotic Drug Screening

Medicine & Life Sciences

• Atherosclerosis 19%
• Chemical Models 91%
• cobaltous chloride 87%
• Control Groups 6%
• Drug Discovery 12%
• Hypoxia 48%
• In Vitro Techniques 5%
• Lipid Droplets 28%
• Lipids 16%
• Macrophages 42%
• oil red O 16%
• oxidized low density lipoprotein 12%
• Preclinical Drug Evaluations 72%
• Therapeutics 4%

Chemical Compounds

• Anti Atherosclerosis 100%
• Chemical Transformation 7%
• Chloride 35%
• Drug 32%
• Foam 55%
• Lipid 25%
• Lipoprotein 13%
• Oil Red O 20%