Clinical value of FDG PET or PET/CT in urinary bladder cancer: A systemic review and meta-analysis

Yu Yu Lu, Jin Hua Chen, Ji An Liang, Hsin Yi Wang, Cheng Chieh Lin, Wan Yu Lin, Chia Hung Kao

研究成果: 雜誌貢獻文章同行評審

86 引文 斯高帕斯(Scopus)

摘要

Aim: The purpose of the current study was to conduct a systemic review and meta-analysis of the published literature to evaluate the diagnostic accuracy of FDG PET or PET/CT in urinary bladder cancer. Materials and methods: The authors conducted a systematic MEDLINE search of articles published between January 2000 and December 2010. Two reviewers independently assessed the methodological quality of each study. We conducted a meta-analysis of pooled sensitivity and specificity in detecting primary and metastatic lesions of bladder cancer. Results: Six studies met the inclusion criteria. The pooled sensitivity and specificity of PET/CT for primary lesion detection of bladder cancer were 0.90 (95% CI: 0.70-0.99) and 1.00 (95% CI: 0.74-1.00), respectively. The pooled sensitivity and specificity of FDG PET or PET/CT for staging or restaging (metastatic lesions) of bladder cancer were 0.82 (95% CI: 0.72-0.89) and 0.89 (95% CI: 0.81-0.95), respectively. Conclusion: The diagnostic accuracy of FDG PET or PET/CT is good in metastatic lesions of urinary bladder cancer. Due to the small number of patients and limited number of studies analyzed, the diagnostic capability of FDG PET or PET/CT in detection of primary bladder wall lesions could not be assessed.

原文英語
頁(從 - 到)2411-2416
頁數6
期刊European Journal of Radiology
81
發行號9
DOIs
出版狀態已發佈 - 九月 2012
對外發佈

ASJC Scopus subject areas

  • 放射學、核子醫學和影像學

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