Clinical observation of meningitis caused by penicilin-susceptible and -non-susceptible Streptococcus pneumoniae in Taiwanese children

Shih Hsiang Chen, Meng Hsiu Yen, Cheng Hsun Chiu, Dah Chin Yan, Chih Yi Hsu, Tzou Yien Lin

研究成果: 雜誌貢獻文章

2 引文 斯高帕斯(Scopus)

摘要

Aim: To compare differences between clinical features and outcome in bacterial meningitis caused by penicillin-susceptible Streproroccus pneumoniae (PSSP) with that caused by penicillin-non-susceptible Streptococcus pneumoniae (PNSP). Methods: All patients < 18 yrs hospitalised with pneumococcal meningitis between January 1984 and December 2002 at Chang Gung Children's Hospital, Taipei were reviewed retrospectively. Results: There were 28 PNSP (63.6%) and 16 PSSP cases of meningitis eligible for the study. The incidence of PNSP meningitis increased significantly over the 8-yr period (p=0.007). Age <4 yrs (78.6% vs 50%), a lower initial white blood count (mean 11.7 vs 19.9 × 109/L), admission to the intensive care unit (70.4% vs 50%) and mortality (28.6% vs 6.3%) were more common in the PNSP group. However, the only significant finding was a lower proportion of polymorphic neutrophils in the CSF of the PNSP meningitis group (p=0.04). Conclusions: There was an increase in PNSP isolates from patients with meningitis over the 8-yr study period. No major differences were observed in clinical or laboratory features or outcome between the PSSP and PNSP group.
原文英語
頁(從 - 到)181-185
頁數5
期刊Annals of Tropical Paediatrics
26
發行號3
DOIs
出版狀態已發佈 - 九月 2006
對外發佈Yes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

指紋 深入研究「Clinical observation of meningitis caused by penicilin-susceptible and -non-susceptible Streptococcus pneumoniae in Taiwanese children」主題。共同形成了獨特的指紋。

  • 引用此