Clinical manifestations of Kikuchi's disease in southern Taiwan

Hsin Liang Yu, Susan Shin Jung Lee, Hung Chin Tsai, Chun Kai Huang, Yao Shen Chen, Hsi Hsin Lin, Shue Ren Wann, Yung Ching Liu, Hui Hwa Tseng

研究成果: 雜誌貢獻文章同行評審

40 引文 斯高帕斯(Scopus)


Histiocytic necrotizing lymphadenitis, or Kikuchi's disease (KD), is a self-limiting cervical lymphadenitis of unknown origin. The diagnosis of KD is problematic due to the lack of specific laboratory tests. This study reviewed the clinical characteristics of 58 patients with KD. Clinical manifestations were of considerable diversity. The mean age of patients was 24.88 ± 7.44 years and there was a female predominance (1.76:1). The most frequent clinical findings were enlarged tender lymph nodes (50%), fever (43%), sore throat (21%), non-productive cough (12%), headache (10%), chills (9%) and rhinorrhea (9%). The most common initial laboratory abnormalities were leukopenia (29%), elevated erythrocyte sedimentation rate (14%), liver function impairment (14%), elevated C-reactive protein level (12%), and anemia (10%). Most patients had unilateral lymph node involvement (79%), which was usually located in the posterior triangle of the cervical lymph nodes (90%). Most patients had no comorbid disease (93%). No recurrence occurred. KD should be included in the differential diagnosis of fever with cervical lymphadenopathy.

頁(從 - 到)35-40
期刊Journal of Microbiology, Immunology and Infection
出版狀態已發佈 - 2月 2005

ASJC Scopus subject areas

  • 微生物學(醫學)
  • 免疫學和過敏
  • 免疫學與微生物學 (全部)


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