Chronic cough and obstructive sleep apnoea in a sleep laboratory-based pulmonary practice

Tsai Yu Wang, Yu Lun Lo, Wen Te Liu, Shu Min Lin, Ting Yu Lin, Chih Hsi Kuo, Fu Tsai Chung, Pai Chien Chou, Po Jui Chang, Yung Lun Ni, Shu Chuan Ho, Horng Chyuan Lin, Chun Hua Wang, Chih Teng Yu, Han Pin Kuo

研究成果: 雜誌貢獻文章

14 引文 斯高帕斯(Scopus)

摘要

Background: Obstructive sleep apnoea (OSA) has recently been identified as a possible aetiology for chronic cough. The aim of this study was to compare the incidence of chronic cough between patients with and without OSA and the impact of continuous positive airway pressure (CPAP) treatment in resolving chronic cough.Methods: Patients referred to the sleep laboratory from January 2012 to June 2012 were retrospectively enrolled. Clinical data, treatment course and resolution of chronic cough were analysed. Specifically, gastro-oesophageal reflux (GERD), upper airway cough syndrome, asthma, apnoea-hypopnoea index and the impact of CPAP treatment on chronic cough were assessed.Results: A total of 131 patients were reviewed. The incidence of chronic cough in the OSA group was significantly higher than the non-OSA group (39/99 (39.4%) vs. 4/32 (12.5%), p = 0.005). Both GERD and apnoea-hypopnoea index were significantly associated with chronic cough in univariate analysis. After multivariate logistic regression, GERD was the only independent factor for chronic cough. Moreover, the resolution of chronic cough was more significant in the OSA patients with CPAP treatment compared with those not receiving CPAP treatment (12/18 (66.7%) vs. 2/21 (9.5%), p = 0.010).Conclusion: The incidence of chronic cough was significantly higher in the OSA patients. In addition, CPAP treatment significantly improved chronic cough. Therefore, OSA may be a contributory factor to chronic cough.
原文英語
文章編號24
期刊Cough
9
發行號1
DOIs
出版狀態已發佈 - 十一月 5 2013

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Pulmonary and Respiratory Medicine

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    Wang, T. Y., Lo, Y. L., Liu, W. T., Lin, S. M., Lin, T. Y., Kuo, C. H., Chung, F. T., Chou, P. C., Chang, P. J., Ni, Y. L., Ho, S. C., Lin, H. C., Wang, C. H., Yu, C. T., & Kuo, H. P. (2013). Chronic cough and obstructive sleep apnoea in a sleep laboratory-based pulmonary practice. Cough, 9(1), [24]. https://doi.org/10.1186/1745-9974-9-24