Chromosome Translocation in Peripheral Neuroepithelioma

Jacqueline Whang-Peng, Timothy J. Triche, Turid Knutsen, James Miser, Edwin C. Douglass, Mark A. Israel

研究成果: 雜誌貢獻文章同行評審

324 引文 斯高帕斯(Scopus)

摘要

PERIPHERAL neuroepithelioma (peripheral neuroblastoma) is an uncommon malignant tumor of the peripheral nervous system with a histologic appearance similar to that of classical childhood neuroblastoma.1 2 3 In contrast to neuroblastoma, it typically presents in older children and young adults, it can be associated with peripheral nerves, and it spares the adrenal glands and sympathetic ganglia. We have studied both tumor specimens and tumor-cell lines from two patients with peripheral neuroepithelioma; in each case, we found these karyotypes to include an rcp(11;22)(q24;q12) indistinguishable from the one that has been reported in Ewing's sarcoma.4,5 This finding supports the hypothesis that these two entities.
原文英語
頁(從 - 到)584-585
頁數2
期刊New England Journal of Medicine
311
發行號9
DOIs
出版狀態已發佈 - 八月 30 1984
對外發佈Yes

ASJC Scopus subject areas

  • Medicine(all)

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