Choroid plexus tumors in childhood - Histopathologic study and clinico-pathological correlation

Donald M. Ho, Tai-Tong Wong, Hung Chang Liu

研究成果: 雜誌貢獻文章同行評審

36 引文 斯高帕斯(Scopus)

摘要

Choroid plexus tumors are rare and account for only 2.3% (8/352) of primary childhood intracranial neoplasms in our series. Most of our patients were under 2 years of age. The tumors had a predilection for the lateral ventricle. Calcification was found in half of these tumors, and ossification was seen in 1 case. Histological features of malignancy including invasion, loss of differentiation, and severe nuclear pleomorphism pointed to a poor prognosis. Such features were found in 2 cases. Neither a large number of mitoses nor necrosis was a constant feature in cases of malignancy. Transthyretin, a marker for choroid plexus tumors, was positive in all cases. However, negative S-100 or positive carcinoembryonic antigen was not necessarily associated with a more aggressive histological pattern. All the papillomas could be totally resected without recurrence, and all the patients with carcinoma died within a few months.

原文英語
頁(從 - 到)437-441
頁數5
期刊Child's Nervous System
7
發行號8
DOIs
出版狀態已發佈 - 十二月 1 1991
對外發佈

ASJC Scopus subject areas

  • 兒科、圍產兒和兒童健康
  • 神經病學(臨床)

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