Chiral liquid crystals as biosensing platforms

Mon Juan Lee, Yu Chien Sung, Yu Cheng Hsiao, Wei Lee

研究成果: 書貢獻/報告類型會議貢獻

4 引文 斯高帕斯(Scopus)

摘要

The texture observation has long been the core technique in liquid crystal (LC)-based bioassays. Its working principle stems from the dark-to-bright texture change induced by the interruption of the initially homeotropic alignment in nematic bulks or from the radial-to-bipolar configuration transition in LC droplets in the presence of biomolecules. One of the drawbacks of this observational scheme, which requires a polarizing optical microscope, is the difficulty in quantitative analysis. In this invited paper, we report on our recent development of alternative optical biosensing techniques based on cholesteric LCs (CLCs) without the use of a polarizer. The increase in structural order in a vertically anchored CLC cell in the quasi-planar state provides a means to allow detection and quantification of the concentration of biomolecules immobilized on the interface between the mesophase and the surfactant DMOAP for LC vertical alignment.
原文英語
主出版物標題Liquid Crystals XX
發行者SPIE
9940
ISBN(電子)9781510602717
DOIs
出版狀態已發佈 - 一月 1 2016
對外發佈Yes
事件Liquid Crystals XX - San Diego, 美国
持續時間: 八月 28 2016八月 30 2016

會議

會議Liquid Crystals XX
國家美国
城市San Diego
期間8/28/168/30/16

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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