Characterization of class 1 integrons and gene cassettes in clinical isolates of Klebsiella pneumoniae from Taiwan

Chung Yu Chang, Yu Ti Fang, Shih Meng Tsai, Lin Li Chang, Wen Liang Yu

研究成果: 雜誌貢獻文章同行評審

26 引文 斯高帕斯(Scopus)

摘要

We surveyed the prevalence and contents of class 1 integrons in clinical Klebsiella pneumoniae isolates collected from Kaohsiung, Taiwan, during 2 periods (1993 and 2004). Class 1 integrons were present in 78 isolates (34.2%) from 1993 (n = 228) and 129 (32.9%) from 2004 (n = 392) and contained varied gene cassette number, type, and array. We found 2 atypical sul3-associated class 1 integrons and identified 26 different gene cassettes, including an aac(6′)-Ib-cr cassette here firstly described in K. pneumoniae from Taiwan. The continuing evolution of class 1 integrons is threatening to undermine the effectiveness of antimicrobial therapy for K. pneumoniae.

原文英語
頁(從 - 到)214-216
頁數3
期刊Diagnostic Microbiology and Infectious Disease
65
發行號2
DOIs
出版狀態已發佈 - 10月 2009

ASJC Scopus subject areas

  • 微生物學(醫學)
  • 傳染性疾病

指紋

深入研究「Characterization of class 1 integrons and gene cassettes in clinical isolates of Klebsiella pneumoniae from Taiwan」主題。共同形成了獨特的指紋。

引用此