Characteristics of an alternative antibacterial biomaterial for mouthwash in the absence of alcohol

Chen Ying Su, Chia Chun Chen, Hsuan Yu Chen, Chun Pin Lin, Feng Huei Lin, Hsu Wei Fang

研究成果: 雜誌貢獻文章

3 引文 斯高帕斯(Scopus)

摘要

Background/purpose: The purpose of this study was to investigate whether poly-gamma-glutamic acid (γ-PGA), a naturally derived biomaterial, was suitable as an alternative antibacterial mouthwash in the absence of alcohol. Materials and methods: Three bacterial strains, Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa, were used for testing the antibacterial activity of mouthwashes. In addition, cell viability, cytotoxicity, and genotoxicity experiments were conducted for testing the toxicity of mouthwashes. Results: We demonstrated that 10000 ppm of γ-PGA without alcohol could efficiently inhibit 99% of bacterial growth. In addition, γ-PGA did not cause any cytotoxicity or genotoxicity. Conclusion: 10000 ppm of γ-PGA in an alcohol-free mouthwash is an alternative biomaterial for mouthwashes.
原文英語
頁(從 - 到)192-197
頁數6
期刊Journal of Dental Sciences
14
發行號2
DOIs
出版狀態已發佈 - 六月 1 2019
對外發佈Yes

ASJC Scopus subject areas

  • Dentistry(all)

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