Characteristics of amebic liver abscess in patients with or without human immunodeficiency virus

Kuan Jung Chen, Chin Hui Yang, Yi Chun Lin, Hsin Yi Liu, Say Tsung Liao, Yuarn Jang Lee

研究成果: 雜誌貢獻文章

5 引文 斯高帕斯(Scopus)

摘要

Background and purpose: Amebic liver abscess (ALA) is the most common extra-intestinal amebiasis. This study was performed to review the clinical features of patients with amebic liver abscesses and compare them in Taiwanese patients with or without human immunodeficiency virus (HIV). Methods: The medical charts of 27 inpatients with ALA treated at the Taipei Medical University Hospital, Taipei, Taiwan, were retrospectively analyzed. ALA was defined as positive findings of indirect hemagglutination test (IHA) and imaging study. Patients were divided into 2 groups according to their HIV infection status. Results: The most common clinical symptoms were fever (89.9%) and abdominal pain (81%). The mean white blood cell count in HIV-uninfected patients was significantly higher than in infected patients (17,830 ± 4,722/μL vs 11,549 ± 5,325/μL; p < 0.01). The aspartate aminotransferase levels were significantly lower in HIV-infected patients than in uninfected patients (85.7 ± 59.1 IU/L vs 31.7 ± 21.2 IU/L; p < 0.01). Three HIV-uninfected patients and 10 infected patients had IHA titer >1:1024 (p < 0.05). The duration of hospital stay was longer for HIV-uninfected patients than for infected patients (24.8 ± 14.6 days vs 11.6 ± 5.9 days; p <0.05) Conclusions: HIV-infected patients with ALA had a more insidious onset of illness, significantly lower white cell count and liver enzymes, and shorter duration of hospital stay than uninfected patients. Physicians should be alert to ALA for early diagnosis and treatment.

原文英語
頁(從 - 到)500-504
頁數5
期刊Journal of Microbiology, Immunology and Infection
42
發行號6
出版狀態已發佈 - 十二月 1 2009

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology and Microbiology(all)
  • Microbiology (medical)
  • Infectious Diseases

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