Characteristics of acoustic wave propagation in dermis for the diagnosis of the superficial tissue damage in radiation therapy

Chung Wei Lyu, Hsian-Jenn Wang, Lee Cheng Peng, Chien Chou

研究成果: 雜誌貢獻Conference article

1 引文 (Scopus)

摘要

Measurement of tissue radiation damage quantitatively in radiation therapy is very important to optimize the therapeutic treatment. Ionized radiation induces homogenization of the extracellular matrix which is synthesized by fibroblast and the randomization of the orientation of the collagen fibers in dermis. If the dermis is exposed by ionized radiation, a thermal acoustic shear wave which propagates in dermis becomes harmonic wave; Otherwise, an inharmonic wave is expected because of inhomogeneous and the anisotropic properties of dermis. A polarized optical heterodyne interferometer was setup in order to measure the transverse displacement of the shear wave in order to analyze the propagation mode of the shear wave in dermis. The detection sensitivity of the displacement was 1 nm and the dynamic range was 300 nm in this arrangement. The lowest dose that can be detected by the exposure of 4 MeV radiation on porcine dermis was 1 cGy.

原文英語
頁(從 - 到)248-254
頁數7
期刊Proceedings of SPIE - The International Society for Optical Engineering
4082
出版狀態已發佈 - 一月 1 2000
對外發佈Yes
事件Optical Sensing, Imaging, and Manipulation for Biological and Biomedical Applications - Taipei, Taiwan
持續時間: 七月 26 2000七月 28 2000

指紋

Acoustic wave propagation
Radiation Therapy
Shear waves
Radiotherapy
Acoustic Waves
Wave Propagation
S waves
radiation therapy
wave propagation
Damage
Tissue
damage
Radiation
acoustics
radiation
propagation modes
Radiation damage
fibroblasts
Fibroblasts
collagens

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

引用此文

@article{85456641365b46658bf9adc5be70f822,
title = "Characteristics of acoustic wave propagation in dermis for the diagnosis of the superficial tissue damage in radiation therapy",
abstract = "Measurement of tissue radiation damage quantitatively in radiation therapy is very important to optimize the therapeutic treatment. Ionized radiation induces homogenization of the extracellular matrix which is synthesized by fibroblast and the randomization of the orientation of the collagen fibers in dermis. If the dermis is exposed by ionized radiation, a thermal acoustic shear wave which propagates in dermis becomes harmonic wave; Otherwise, an inharmonic wave is expected because of inhomogeneous and the anisotropic properties of dermis. A polarized optical heterodyne interferometer was setup in order to measure the transverse displacement of the shear wave in order to analyze the propagation mode of the shear wave in dermis. The detection sensitivity of the displacement was 1 nm and the dynamic range was 300 nm in this arrangement. The lowest dose that can be detected by the exposure of 4 MeV radiation on porcine dermis was 1 cGy.",
author = "Lyu, {Chung Wei} and Hsian-Jenn Wang and Peng, {Lee Cheng} and Chien Chou",
year = "2000",
month = "1",
day = "1",
language = "English",
volume = "4082",
pages = "248--254",
journal = "Proceedings of SPIE - The International Society for Optical Engineering",
issn = "0277-786X",
publisher = "SPIE",

}

TY - JOUR

T1 - Characteristics of acoustic wave propagation in dermis for the diagnosis of the superficial tissue damage in radiation therapy

AU - Lyu, Chung Wei

AU - Wang, Hsian-Jenn

AU - Peng, Lee Cheng

AU - Chou, Chien

PY - 2000/1/1

Y1 - 2000/1/1

N2 - Measurement of tissue radiation damage quantitatively in radiation therapy is very important to optimize the therapeutic treatment. Ionized radiation induces homogenization of the extracellular matrix which is synthesized by fibroblast and the randomization of the orientation of the collagen fibers in dermis. If the dermis is exposed by ionized radiation, a thermal acoustic shear wave which propagates in dermis becomes harmonic wave; Otherwise, an inharmonic wave is expected because of inhomogeneous and the anisotropic properties of dermis. A polarized optical heterodyne interferometer was setup in order to measure the transverse displacement of the shear wave in order to analyze the propagation mode of the shear wave in dermis. The detection sensitivity of the displacement was 1 nm and the dynamic range was 300 nm in this arrangement. The lowest dose that can be detected by the exposure of 4 MeV radiation on porcine dermis was 1 cGy.

AB - Measurement of tissue radiation damage quantitatively in radiation therapy is very important to optimize the therapeutic treatment. Ionized radiation induces homogenization of the extracellular matrix which is synthesized by fibroblast and the randomization of the orientation of the collagen fibers in dermis. If the dermis is exposed by ionized radiation, a thermal acoustic shear wave which propagates in dermis becomes harmonic wave; Otherwise, an inharmonic wave is expected because of inhomogeneous and the anisotropic properties of dermis. A polarized optical heterodyne interferometer was setup in order to measure the transverse displacement of the shear wave in order to analyze the propagation mode of the shear wave in dermis. The detection sensitivity of the displacement was 1 nm and the dynamic range was 300 nm in this arrangement. The lowest dose that can be detected by the exposure of 4 MeV radiation on porcine dermis was 1 cGy.

UR - http://www.scopus.com/inward/record.url?scp=0033697832&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033697832&partnerID=8YFLogxK

M3 - Conference article

AN - SCOPUS:0033697832

VL - 4082

SP - 248

EP - 254

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

SN - 0277-786X

ER -