Enterobacter cloacae (n = 110) isolates from a district hospital in Taiwan were screened for extended-spectrum β-lactamases (ESBLs). In total, 17 ESBL-producers were identified, based on the combination-disk synergy test using cefotaxime and ceftazidime ± clavulanic acid. Investigation of ESBL genes in 33 ceftazidime-resistant isolates revealed the SHV-12 gene in the same 17 ESBL-producers. In addition, one isolate also carried the CTX-M-3 gene, and two isolates also carried the CTX-M-9 gene. No major epidemic clone of ESBL-producers was identified by pulsed-field gel electrophoresis. Routine screening for the ESBL phenotype, focusing on ceftazidime-resistant E. cloacae, should be undertaken in this area.
ASJC Scopus subject areas
- Microbiology (medical)
Yu, W-L., Cheng, K-C., Chi, C. J., Chen, H. E., Chuang, Y. C., & Wu, L. T. (2006). Characterisation and molecular epidemiology of extended-spectrum β-lactamase-producing Enterobacter cloacae isolated from a district teaching hospital in Taiwan. Clinical Microbiology and Infection, 12(6), 579-582. https://doi.org/10.1111/j.1469-0691.2006.01384.x