Changes in arachidonate metabolism in aortas and platelets in aging rats

Wen Chang Chang, Hsin Hsiung Tai

研究成果: 雜誌貢獻文章

11 引文 斯高帕斯(Scopus)

摘要

Prostacyclin formation by aortas, thromboxane biosynthesis and 12-lipoxygenase pathway in platelets as a function of age was investigated. Our results indicate an age-related decrease in prostacyclin production by aortas, while no significant change in thromboxane biosynthesis in platelets from mature (12 month old) to senescent (24 month old) rats was observed. Evidence is also presented indicating a decrease in 12-L-hydroperoxy-5,8,10,14-eicosatetraenoic acid (12-HPETE) peroxidase activity in platelets as a function of age.

原文英語
頁(從 - 到)149-157
頁數9
期刊Prostaglandins, Leukotrienes and Medicine
12
發行號2
DOIs
出版狀態已發佈 - 1983
對外發佈Yes

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology
  • Physiology

指紋 深入研究「Changes in arachidonate metabolism in aortas and platelets in aging rats」主題。共同形成了獨特的指紋。

  • 引用此