Cerebro-Cerebellar Pathways for Verbal Working Memory

Monika Sobczak-Edmans, Yu-Chun Lo, Yung-Chin Hsu, Yu-Jen Chen, Fu Yu Kwok, Kai-Hsiang Chuang, Wen-Yih Isaac Tseng, S H Annabel Chen

研究成果: 雜誌貢獻文章

摘要

The current study examined the structural and functional connectivity of the cerebro-cerebellar network of verbal working memory as proposed by Chen and Desmond (2005a). Diffusion spectrum imaging was employed to establish structural connectivity between cerebro-cerebellar regions co-activated during a verbal working memory task. The inferior frontal gyrus, inferior parietal lobule, pons, thalamus, superior cerebellum and inferior cerebellum were used as regions of interest to reconstruct and segment the contralateral white matter cerebro-cerebellar circuitry. The segmented pathways were examined further to establish the relationship between structural and effective connectivity as well as the relationship between structural connectivity and verbal working memory performance. No direct relationship between structural and effective connectivity was found but the results demonstrated that structural connectivity is indirectly related to effective connectivity as DCM models that resembled more closely with underlying white matter pathways had a higher degree of model inference confidence. Additionally, it was demonstrated that the structural connectivity of the ponto-cerebellar tract was associated with individual differences in response time for verbal working memory. The findings of the study contribute to further our understanding of the relationship between structural and functional connectivity and the impact of variability in verbal working memory performance.
原文英語
頁(從 - 到)530
期刊Frontiers in Human Neuroscience
12
DOIs
出版狀態已發佈 - 2019

指紋

Short-Term Memory
Cerebellum
Parietal Lobe
Pons
Prefrontal Cortex
Thalamus
Individuality
Reaction Time
White Matter

引用此文

Sobczak-Edmans, M., Lo, Y-C., Hsu, Y-C., Chen, Y-J., Kwok, F. Y., Chuang, K-H., ... Chen, S. H. A. (2019). Cerebro-Cerebellar Pathways for Verbal Working Memory. Frontiers in Human Neuroscience, 12, 530. https://doi.org/10.3389/fnhum.2018.00530

Cerebro-Cerebellar Pathways for Verbal Working Memory. / Sobczak-Edmans, Monika; Lo, Yu-Chun; Hsu, Yung-Chin; Chen, Yu-Jen; Kwok, Fu Yu; Chuang, Kai-Hsiang; Tseng, Wen-Yih Isaac; Chen, S H Annabel.

於: Frontiers in Human Neuroscience, 卷 12, 2019, p. 530.

研究成果: 雜誌貢獻文章

Sobczak-Edmans, M, Lo, Y-C, Hsu, Y-C, Chen, Y-J, Kwok, FY, Chuang, K-H, Tseng, W-YI & Chen, SHA 2019, 'Cerebro-Cerebellar Pathways for Verbal Working Memory', Frontiers in Human Neuroscience, 卷 12, 頁 530. https://doi.org/10.3389/fnhum.2018.00530
Sobczak-Edmans, Monika ; Lo, Yu-Chun ; Hsu, Yung-Chin ; Chen, Yu-Jen ; Kwok, Fu Yu ; Chuang, Kai-Hsiang ; Tseng, Wen-Yih Isaac ; Chen, S H Annabel. / Cerebro-Cerebellar Pathways for Verbal Working Memory. 於: Frontiers in Human Neuroscience. 2019 ; 卷 12. 頁 530.
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