Cerebral columnar organization of the first nociceptive component induced by CO2 laser on the tail of the rat

Fu-Shan Jaw, Yu-Chieh Jill Kao, Chih-Ping Chen, Wen-Li Liao

研究成果: 雜誌貢獻文章

5 引文 斯高帕斯(Scopus)

摘要

The somatotopic map of the first nociceptive component in the primary somatosensory cortex (S1) is still unclear. In this study, a CO2 laser was applied to the tail of the rat to induce nociception without the interference from large myelinated (Aβ) fibers. Thus, only noxious fibers could be activated. Two-dimensional current-source-density analysis was used to analyze the evoked field potentials. Using this method, the nociceptive responses of Aδ-fibers in S1 were verified, and the somatotopic map of the first nociceptive component in S1 was identified. We found that whether light touch or laser-induced nociception was applied to the tail of the rat, the responsive topography in S1 was consistent. Discrimination of these two modalities was achieved vertically in the same column; the deeper layer represented the nociceptive response while the superficial layer encoded the response to light touch. This is quite different from that of a primate brain. © 2009 IBRO.
原文英語
頁(從 - 到)945-950
頁數6
期刊Neuroscience
158
發行號2
DOIs
出版狀態已發佈 - 2009
對外發佈Yes

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