摘要

Background: Chronic central nervous system (CNS) infections have been found to associate with cerebrovascular complications. Acute CNS infections are more common than chronic CNS infections, but whether they could increase the risk of vascular diseases has not been studied. Methods: The study cohort comprised all adult patients with diagnoses of CNS infections from Taiwan National Health Insurance Research Database during 2000-2009 (n = 533). The comparison group were matched by age, sex, urbanization, diagnostic year, and vascular risk factors of cases (cases and controls = 1:5). Patients were tracked for at least 1 year. Kaplan-Meier analysis was used to compare the risk of stroke and acute myocardial infarction (AMI) after adjusting censoring subjects. Results: After adjusting the patients demographic characteristics and comorbidities, the risk of patients with CNS infections developing stroke was 2.75-3.44 times greater than their comparison group. More than 70% of the stroke events were occurring within 1 year after CNS infections. The risk of AMI was not found as we compared patients with and without CNS infections. Conclusions: The population-based cohort study suggested that adult patients with CNS infections have higher risk to develop stroke but not AMI, and the risk is marked within a year after infections.
原文英語
頁(從 - 到)241-248
頁數8
期刊Acta Neurologica Scandinavica
128
發行號4
DOIs
出版狀態已發佈 - 十月 2013

Keywords

  • Cerebrovascular diseases
  • Infections
  • Strokes

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

指紋 深入研究「Central nervous system infections and stroke: a population-based analysis」主題。共同形成了獨特的指紋。

  • 引用此