Cell migration rate on poly(ε-caprolactone)/poly(ethylene glycol) diblock copolymers and correlation with the material sliding angle

Shan Hui Hsu, Cheng Ming Tang, Jeng Jiann Chiu, Tien Chi Liao, Chu Chieh Lin, Hiroo Iwata

研究成果: 雜誌貢獻文章同行評審

12 引文 斯高帕斯(Scopus)

摘要

The nanostructure of a biomaterial surface has strong influence on cell behavior. The migration of cells on nanostructured surfaces, however, has not been investigated so far. In this study, we used PCL/PEG diblock copolymers as model surfaces to examine the effect of nanoislands on migration of different cells, including fibroblasts and endothelial cells. The water sliding angle of the substrates was measured. The cell migration rate was examined under a real-time optical microscope. It was found that a greater cell migration rate correlated with the smaller sliding angle of the substrate.

原文英語
頁(從 - 到)482-490
頁數9
期刊Macromolecular Bioscience
7
發行號4
DOIs
出版狀態已發佈 - 四月 10 2007
對外發佈Yes

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biomaterials
  • Polymers and Plastics
  • Materials Chemistry

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