Cardiovascular risk and comorbidities in patients with rosacea: A systematic review and meta-analysis

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1 引文 斯高帕斯(Scopus)

摘要

The association between rosacea and cardiovascular disease remains controversial. A systematic review and meta-analysis of the literature, from inception to 15 February 2020, was performed to compare cardiovascular risk and comorbidities in individuals with and without rosacea. Twelve studies, involving 40,752 patients with rosacea, were included. Compared with con-trols, patients with rosacea had higher systolic blood pressure (standardized mean difference (SMD) 0.293, 95% confidence interval (CI) 0.054–0.532), diastolic blood pressure (SMD 0.309, 95% CI 0.003–0.615), to-tal cholesterol (SMD 1.147, 95% CI 0.309–1.984), low-density lipoprotein (SMD 0.792, 95% CI 0.174–1.409), C-reactive protein (SMD 0.26, 95% CI 0.099–0.421), greater epicardial fat thickness (SMD 1.945, 95% CI 1.595–2.296), and higher incidence of hypertension (odds ratio (OR) 1.204, 95% CI 1.097–1.332) and insulin resistance (OR 2.338, 95% CI 1.187–4.605). This study reveals that patients with rosacea are predis-posed to increased subclinical cardiovascular risk.

原文英語
文章編號adv00300
頁(從 - 到)1-7
頁數7
期刊Acta Dermato-Venereologica
100
發行號17
DOIs
出版狀態已發佈 - 2020

ASJC Scopus subject areas

  • 皮膚科

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