Cancer risk among gingivitis and periodontitis patients: A nationwide cohort study

B. W. Wen, Chin Shaw Stella Tsai, Cheng Li Lin, Yen Jung Chang, C. F. Lee, Chung-Huei Hsu, Chia Hung Kao

研究成果: 雜誌貢獻文章

34 引文 (Scopus)

摘要

Aim: Periodontal disease encompasses gingivitis and periodontitis, which exerts systemic effects. We conducted a population-based study to evaluate the association between periodontal disease and the risk of cancer. Methods: We used insurance claims data from 1997 to 2010, accessing a database of 1 million randomly selected insurants in Taiwan. All patients were older than 20 and newly diagnosed with periodontitis between 1 January 1997 and 31 December 2010. The comparison cohort comprised patients older than 20, who were newly diagnosed with gingivitis in the same period. Both cohorts were followed until a cancer diagnosis, lost to follow-up, death, termination of insurance, or the end of 2010. Results: The incidence rate of cancer was 1.14 times higher in the study cohort than in the comparison cohort [confidence interval (CI) = 1.11-1.17]. The adjusted hazard ratio (HR) was 1.05 (95% CI = 1.00-1.11). A multivariable analysis showed that the periodontitis patients exhibited an elevated risk of developing oral cancer (adjusted HR = 1.79, 95% CI = 1.42-2.25). Conclusion: The findings indicated that patients in the periodontitis cohort exhibited a higher risk of developing oral cancer than those in the gingivitis cohort.
原文英語
文章編號hct248
頁(從 - 到)283-290
頁數8
期刊QJM
107
發行號4
DOIs
出版狀態已發佈 - 2014

指紋

Gingivitis
Periodontitis
Cohort Studies
Mouth Neoplasms
Periodontal Diseases
Confidence Intervals
Insurance
Neoplasms
Lost to Follow-Up
Taiwan
Databases
Incidence
Population

ASJC Scopus subject areas

  • Medicine(all)

引用此文

Wen, B. W., Tsai, C. S. S., Lin, C. L., Chang, Y. J., Lee, C. F., Hsu, C-H., & Kao, C. H. (2014). Cancer risk among gingivitis and periodontitis patients: A nationwide cohort study. QJM, 107(4), 283-290. [hct248]. https://doi.org/10.1093/qjmed/hct248

Cancer risk among gingivitis and periodontitis patients : A nationwide cohort study. / Wen, B. W.; Tsai, Chin Shaw Stella; Lin, Cheng Li; Chang, Yen Jung; Lee, C. F.; Hsu, Chung-Huei; Kao, Chia Hung.

於: QJM, 卷 107, 編號 4, hct248, 2014, p. 283-290.

研究成果: 雜誌貢獻文章

Wen, BW, Tsai, CSS, Lin, CL, Chang, YJ, Lee, CF, Hsu, C-H & Kao, CH 2014, 'Cancer risk among gingivitis and periodontitis patients: A nationwide cohort study', QJM, 卷 107, 編號 4, hct248, 頁 283-290. https://doi.org/10.1093/qjmed/hct248
Wen, B. W. ; Tsai, Chin Shaw Stella ; Lin, Cheng Li ; Chang, Yen Jung ; Lee, C. F. ; Hsu, Chung-Huei ; Kao, Chia Hung. / Cancer risk among gingivitis and periodontitis patients : A nationwide cohort study. 於: QJM. 2014 ; 卷 107, 編號 4. 頁 283-290.
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