C-reactive protein positively correlates with metabolic syndrome in kidney transplantation patients

Ming Che Lee, Guan Jin Ho, Jing Liang Chen, Bang Gee Hsu

研究成果: 雜誌貢獻文章同行評審

摘要

Objective: C-reactive protein (CRP) is an independent risk factor for renal allograft loss and predicts all-cause mortality in kidney transplantation patients. Metabolic syndrome has also been associated with increased mortality in kidney transplantation patients. The aim of this study was to investigate the relationship between CRP and metabolic syndrome in kidney transplantation patients. Materials and Methods: Fasting blood samples were obtained from 55 kidney transplantation patients. Metabolic syndrome and its components were defined using diagnostic criteria from the International Diabetes Federation. Results: In total, 13 kidney transplantation patients (23.6%) had metabolic syndrome. Fasting CRP levels positively correlated with metabolic syndrome (p = 0.001). Univariate linear regression analysis indicated that fasting serum CRP values were positively correlated with body weight (p = 0.001), waist circumference (p = 0.008), body mass index (p < 0.001), and body fat mass (p = 0.042). Multivariate forward stepwise linear regression analysis of the significant variables showed that body mass index (β = 0.455, R2 = 0.207, p < 0.001) was an independent predictor of serum CRP levels in kidney transplantation patients. Conclusion: CRP level positively correlated with metabolic syndrome in kidney transplantation patients. Body mass index was an independent predictor of serum CRP levels in kidney transplantation patients.

原文英語
頁(從 - 到)131-136
頁數6
期刊Tzu Chi Medical Journal
22
發行號3
DOIs
出版狀態已發佈 - 9月 2010
對外發佈

ASJC Scopus subject areas

  • 醫藥 (全部)

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