Brain stimulation improves cognitive control by modulating medial-frontal activity and preSMA-vmPFC functional connectivity

Jiaxin Yu, Philip Tseng, Daisy L. Hung, Shih Wei Wu, Chi Hung Juan

研究成果: 雜誌貢獻文章同行評審

40 引文 斯高帕斯(Scopus)

摘要

Previous research has demonstrated that brain stimulation can improve inhibitory control. However, the neural mechanisms underlying such artificially induced improvement remain unclear. In this study, by coupling anodal transcranial direct current stimulation (atDCS) with functional MRI, we found that atDCS over preSMA effectively improved stopping speed, which was associated with increased BOLD response in the preSMA and ventromedial prefrontal cortex (vmPFC). Furthermore, such atDCS-induced BOLD increase in vmPFC was positively correlated with participants' improvement in stopping efficiency, and the functional connectivity between preSMA and vmPFC increased during successful stop. These results suggest that the rapid behavioral improvement from preSMA brain stimulation involves modulated medial-frontal activity and preSMA-vmPFC functional connectivity.
原文英語
頁(從 - 到)4004-4015
頁數12
期刊Human Brain Mapping
36
發行號10
DOIs
出版狀態已發佈 - 10月 1 2015

ASJC Scopus subject areas

  • 神經病學(臨床)
  • 解剖學
  • 神經內科
  • 放射學、核子醫學和影像學
  • 放射與超音波技術

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