TY - JOUR
T1 - Brain stem cavernous malformations
AU - Huang, A. P H
AU - Chen, Jui Sheng
AU - Yang, Chi Cheng
AU - Wang, Kuo Chuan
AU - Yang, Shih Hung
AU - Lai, Dar Ming
AU - Tu, Yong Kwang
PY - 2010/1/1
Y1 - 2010/1/1
N2 - We retrospectively reviewed the clinical experience of 30 patients with brain stem cavernous malformations (BSCM) treated operatively and non-operatively at our hospital between 1983 and 2005 to elucidate the natural history of BSCM and the factors that affect surgical outcome. Inpatient charts, imaging studies, operative records, and follow-up results were evaluated. The average follow up was 48.5 months. Twenty-two patients (73.3%) received surgical extirpation and of these 86.4% improved or stabilized and 13.6% deteriorated with permanent or severe morbidity. There was no mortality. Size, preoperative status, and surgical timing were factors related to surgical outcome. In the non-operative group, 50% of the patients were the same or better, 25% deteriorated, and 25% died. With appropriate patient selection, resection of BSCM can be achieved with acceptable morbidity compared with the ominous natural history of these lesions.
AB - We retrospectively reviewed the clinical experience of 30 patients with brain stem cavernous malformations (BSCM) treated operatively and non-operatively at our hospital between 1983 and 2005 to elucidate the natural history of BSCM and the factors that affect surgical outcome. Inpatient charts, imaging studies, operative records, and follow-up results were evaluated. The average follow up was 48.5 months. Twenty-two patients (73.3%) received surgical extirpation and of these 86.4% improved or stabilized and 13.6% deteriorated with permanent or severe morbidity. There was no mortality. Size, preoperative status, and surgical timing were factors related to surgical outcome. In the non-operative group, 50% of the patients were the same or better, 25% deteriorated, and 25% died. With appropriate patient selection, resection of BSCM can be achieved with acceptable morbidity compared with the ominous natural history of these lesions.
KW - Brain stem hemorrhage
KW - Cavernoma
KW - Cavernous malformation
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U2 - 10.1016/j.jocn.2009.06.009
DO - 10.1016/j.jocn.2009.06.009
M3 - Article
C2 - 20005720
AN - SCOPUS:72449165030
VL - 17
SP - 74
EP - 79
JO - Journal of Clinical Neuroscience
JF - Journal of Clinical Neuroscience
SN - 0967-5868
IS - 1
ER -