Blood and seminal plasma mercury levels and predatory fish intake in relation to low semen quality

Chin En Ai, Ching Jen Li, Ming Chien Tsou, Jun Lin Chen, Hsing Cheng Hsi, Ling Chu Chien

研究成果: 雜誌貢獻文章

摘要

Declining human sperm quality has been demonstrated in several recent studies. Age, environmental factors, and nutritional factors can affect semen quality. Mercury (Hg) is considered a male reproductive toxicant. Animal studies indicated that exposure to Hg can cause DNA damage, sperm dysfunction, and decreased sperm motility. Some previous studies also revealed that blood Hg levels in infertile or subfertile males were higher than those in normal males. In this study, we recruited 84 male participants from a reproductive medical center and investigated the Hg, lead, and selenium levels in blood and seminal plasma. Participants were divided into two groups, low- and high-quality semen groups, according to the World Health Organization reference values for human semen characteristics. The distribution of blood reproductive hormones and information on participants’ lifestyle and medical history were collected from structured questionnaires. Average Hg levels in blood were 9.3±5.9 versus 8.9±5.9 and in seminal plasma were 1.26±0.61 versus 1.05±0.52 μg/L in the low- and high-quality semen groups, respectively. There was a dose-dependent relationship between blood Hg levels and normal sperm morphology (p=0.02). Participants with predatory fish intake and high blood Hg level had lower sperm with a normal morphology. Therefore, predatory fish intake may be a critical risk factor for elevated Hg levels in males and cause low semen quality
原文英語
期刊Environmental Science and Pollution Research
DOIs
出版狀態已發佈 - 一月 1 2019

指紋

Semen Analysis
Semen
Mercury
Fish
Fishes
Blood
sperm
blood
Spermatozoa
Plasmas
plasma
fish
Sperm Motility
Age Factors
Selenium
Hormones
DNA Damage
World Health Organization
motility
Life Style

ASJC Scopus subject areas

  • Environmental Chemistry
  • Pollution
  • Health, Toxicology and Mutagenesis

引用此文

Blood and seminal plasma mercury levels and predatory fish intake in relation to low semen quality. / Ai, Chin En; Li, Ching Jen; Tsou, Ming Chien; Chen, Jun Lin; Hsi, Hsing Cheng; Chien, Ling Chu.

於: Environmental Science and Pollution Research, 01.01.2019.

研究成果: 雜誌貢獻文章

@article{b05996e6085a49fcaa226830b12e8db8,
title = "Blood and seminal plasma mercury levels and predatory fish intake in relation to low semen quality",
abstract = "Declining human sperm quality has been demonstrated in several recent studies. Age, environmental factors, and nutritional factors can affect semen quality. Mercury (Hg) is considered a male reproductive toxicant. Animal studies indicated that exposure to Hg can cause DNA damage, sperm dysfunction, and decreased sperm motility. Some previous studies also revealed that blood Hg levels in infertile or subfertile males were higher than those in normal males. In this study, we recruited 84 male participants from a reproductive medical center and investigated the Hg, lead, and selenium levels in blood and seminal plasma. Participants were divided into two groups, low- and high-quality semen groups, according to the World Health Organization reference values for human semen characteristics. The distribution of blood reproductive hormones and information on participants’ lifestyle and medical history were collected from structured questionnaires. Average Hg levels in blood were 9.3±5.9 versus 8.9±5.9 and in seminal plasma were 1.26±0.61 versus 1.05±0.52 μg/L in the low- and high-quality semen groups, respectively. There was a dose-dependent relationship between blood Hg levels and normal sperm morphology (p=0.02). Participants with predatory fish intake and high blood Hg level had lower sperm with a normal morphology. Therefore, predatory fish intake may be a critical risk factor for elevated Hg levels in males and cause low semen quality.",
keywords = "Mercury, Predatory fish, Semen quality, Sperm morphology",
author = "Ai, {Chin En} and Li, {Ching Jen} and Tsou, {Ming Chien} and Chen, {Jun Lin} and Hsi, {Hsing Cheng} and Chien, {Ling Chu}",
year = "2019",
month = "1",
day = "1",
doi = "10.1007/s11356-019-04592-6",
language = "English",
journal = "Environmental Science and Pollution Research",
issn = "0944-1344",
publisher = "Springer Science + Business Media",

}

TY - JOUR

T1 - Blood and seminal plasma mercury levels and predatory fish intake in relation to low semen quality

AU - Ai, Chin En

AU - Li, Ching Jen

AU - Tsou, Ming Chien

AU - Chen, Jun Lin

AU - Hsi, Hsing Cheng

AU - Chien, Ling Chu

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Declining human sperm quality has been demonstrated in several recent studies. Age, environmental factors, and nutritional factors can affect semen quality. Mercury (Hg) is considered a male reproductive toxicant. Animal studies indicated that exposure to Hg can cause DNA damage, sperm dysfunction, and decreased sperm motility. Some previous studies also revealed that blood Hg levels in infertile or subfertile males were higher than those in normal males. In this study, we recruited 84 male participants from a reproductive medical center and investigated the Hg, lead, and selenium levels in blood and seminal plasma. Participants were divided into two groups, low- and high-quality semen groups, according to the World Health Organization reference values for human semen characteristics. The distribution of blood reproductive hormones and information on participants’ lifestyle and medical history were collected from structured questionnaires. Average Hg levels in blood were 9.3±5.9 versus 8.9±5.9 and in seminal plasma were 1.26±0.61 versus 1.05±0.52 μg/L in the low- and high-quality semen groups, respectively. There was a dose-dependent relationship between blood Hg levels and normal sperm morphology (p=0.02). Participants with predatory fish intake and high blood Hg level had lower sperm with a normal morphology. Therefore, predatory fish intake may be a critical risk factor for elevated Hg levels in males and cause low semen quality.

AB - Declining human sperm quality has been demonstrated in several recent studies. Age, environmental factors, and nutritional factors can affect semen quality. Mercury (Hg) is considered a male reproductive toxicant. Animal studies indicated that exposure to Hg can cause DNA damage, sperm dysfunction, and decreased sperm motility. Some previous studies also revealed that blood Hg levels in infertile or subfertile males were higher than those in normal males. In this study, we recruited 84 male participants from a reproductive medical center and investigated the Hg, lead, and selenium levels in blood and seminal plasma. Participants were divided into two groups, low- and high-quality semen groups, according to the World Health Organization reference values for human semen characteristics. The distribution of blood reproductive hormones and information on participants’ lifestyle and medical history were collected from structured questionnaires. Average Hg levels in blood were 9.3±5.9 versus 8.9±5.9 and in seminal plasma were 1.26±0.61 versus 1.05±0.52 μg/L in the low- and high-quality semen groups, respectively. There was a dose-dependent relationship between blood Hg levels and normal sperm morphology (p=0.02). Participants with predatory fish intake and high blood Hg level had lower sperm with a normal morphology. Therefore, predatory fish intake may be a critical risk factor for elevated Hg levels in males and cause low semen quality.

KW - Mercury

KW - Predatory fish

KW - Semen quality

KW - Sperm morphology

UR - http://www.scopus.com/inward/record.url?scp=85065714012&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85065714012&partnerID=8YFLogxK

U2 - 10.1007/s11356-019-04592-6

DO - 10.1007/s11356-019-04592-6

M3 - Article

JO - Environmental Science and Pollution Research

JF - Environmental Science and Pollution Research

SN - 0944-1344

ER -