Bladder pain syndrome/interstitial cystitis increase the risk of coronary heart disease

Ho Mei Chen, Ching Chun Lin, Chih Sen Kang, Chun Te Lee, Herng Ching Lin, Shiu Dong Chung

研究成果: 雜誌貢獻文章

9 引文 (Scopus)

摘要

Aim Vascular factor was proposed as being involved in the etiology of bladder pain syndrome/interstitial cystitis (BPS/IC). However, few studies have attempted to investigate the relationship between BPS/IC and cardiovascular disease. This study aimed to investigate the risk of coronary heart disease (CHD) among BPS/IC subjects during a 3-year follow-up period. Methods Data for this retrospective matched-cohort study were retrieved from the Taiwan "Longitudinal Health Insurance Database 2000." There were 752 BPS/IC female subjects in the study cohort and 3,760 randomly selected female subjects in the comparison cohort. We individually tracked each subject for 3 years and identified each subject that received a subsequent diagnosis of CHD during that follow-up period. Results Results showed that incidence rates of CHD during the 3-year follow-up period were 19.50 (95% confidence interval (CI): 14.35-25.95) and 8.87 (95% CI: 7.25-10.74) per 1,000 person-years for the study and comparison cohorts, respectively. The Cox proportional hazards regression suggested that the hazard ratio for CHD in subjects with BPS/IC was 1.65 (95% CI: 1.09-2.48) within the 3-year follow-up period following the index date compared to the comparison subjects after adjusting for monthly income, geographic region, hypertension, diabetes, hyperlipidemia, chronic kidney disease, bladder outlet obstruction, urinary tract infection, chronic pelvic pain, overactive bladder, and number of physician visits during the 3-year follow up period. Conclusions Our study demonstrated an association between BPS/IC and a subsequent CHD diagnosis. We advise clinicians to screen subjects with BPS/IC for modifiable risk factors for CHD. Neurourol. Urodynam. 33:511-515, 2014.
原文英語
頁(從 - 到)511-515
頁數5
期刊Neurourology and Urodynamics
33
發行號5
DOIs
出版狀態已發佈 - 2014

指紋

Interstitial Cystitis
Coronary Disease
Urinary Bladder
Pain
Cohort Studies
Confidence Intervals
Urinary Bladder Neck Obstruction
Overactive Urinary Bladder
Pelvic Pain
Health Insurance
Hyperlipidemias
Taiwan
Chronic Renal Insufficiency
Urinary Tract Infections
Chronic Pain
Cardiovascular Diseases
Databases
Hypertension
Physicians
Incidence

ASJC Scopus subject areas

  • Clinical Neurology
  • Urology
  • Medicine(all)

引用此文

Bladder pain syndrome/interstitial cystitis increase the risk of coronary heart disease. / Chen, Ho Mei; Lin, Ching Chun; Kang, Chih Sen; Lee, Chun Te; Lin, Herng Ching; Chung, Shiu Dong.

於: Neurourology and Urodynamics, 卷 33, 編號 5, 2014, p. 511-515.

研究成果: 雜誌貢獻文章

Chen, Ho Mei ; Lin, Ching Chun ; Kang, Chih Sen ; Lee, Chun Te ; Lin, Herng Ching ; Chung, Shiu Dong. / Bladder pain syndrome/interstitial cystitis increase the risk of coronary heart disease. 於: Neurourology and Urodynamics. 2014 ; 卷 33, 編號 5. 頁 511-515.
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abstract = "Aim Vascular factor was proposed as being involved in the etiology of bladder pain syndrome/interstitial cystitis (BPS/IC). However, few studies have attempted to investigate the relationship between BPS/IC and cardiovascular disease. This study aimed to investigate the risk of coronary heart disease (CHD) among BPS/IC subjects during a 3-year follow-up period. Methods Data for this retrospective matched-cohort study were retrieved from the Taiwan {"}Longitudinal Health Insurance Database 2000.{"} There were 752 BPS/IC female subjects in the study cohort and 3,760 randomly selected female subjects in the comparison cohort. We individually tracked each subject for 3 years and identified each subject that received a subsequent diagnosis of CHD during that follow-up period. Results Results showed that incidence rates of CHD during the 3-year follow-up period were 19.50 (95{\%} confidence interval (CI): 14.35-25.95) and 8.87 (95{\%} CI: 7.25-10.74) per 1,000 person-years for the study and comparison cohorts, respectively. The Cox proportional hazards regression suggested that the hazard ratio for CHD in subjects with BPS/IC was 1.65 (95{\%} CI: 1.09-2.48) within the 3-year follow-up period following the index date compared to the comparison subjects after adjusting for monthly income, geographic region, hypertension, diabetes, hyperlipidemia, chronic kidney disease, bladder outlet obstruction, urinary tract infection, chronic pelvic pain, overactive bladder, and number of physician visits during the 3-year follow up period. Conclusions Our study demonstrated an association between BPS/IC and a subsequent CHD diagnosis. We advise clinicians to screen subjects with BPS/IC for modifiable risk factors for CHD. Neurourol. Urodynam. 33:511-515, 2014.",
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T1 - Bladder pain syndrome/interstitial cystitis increase the risk of coronary heart disease

AU - Chen, Ho Mei

AU - Lin, Ching Chun

AU - Kang, Chih Sen

AU - Lee, Chun Te

AU - Lin, Herng Ching

AU - Chung, Shiu Dong

PY - 2014

Y1 - 2014

N2 - Aim Vascular factor was proposed as being involved in the etiology of bladder pain syndrome/interstitial cystitis (BPS/IC). However, few studies have attempted to investigate the relationship between BPS/IC and cardiovascular disease. This study aimed to investigate the risk of coronary heart disease (CHD) among BPS/IC subjects during a 3-year follow-up period. Methods Data for this retrospective matched-cohort study were retrieved from the Taiwan "Longitudinal Health Insurance Database 2000." There were 752 BPS/IC female subjects in the study cohort and 3,760 randomly selected female subjects in the comparison cohort. We individually tracked each subject for 3 years and identified each subject that received a subsequent diagnosis of CHD during that follow-up period. Results Results showed that incidence rates of CHD during the 3-year follow-up period were 19.50 (95% confidence interval (CI): 14.35-25.95) and 8.87 (95% CI: 7.25-10.74) per 1,000 person-years for the study and comparison cohorts, respectively. The Cox proportional hazards regression suggested that the hazard ratio for CHD in subjects with BPS/IC was 1.65 (95% CI: 1.09-2.48) within the 3-year follow-up period following the index date compared to the comparison subjects after adjusting for monthly income, geographic region, hypertension, diabetes, hyperlipidemia, chronic kidney disease, bladder outlet obstruction, urinary tract infection, chronic pelvic pain, overactive bladder, and number of physician visits during the 3-year follow up period. Conclusions Our study demonstrated an association between BPS/IC and a subsequent CHD diagnosis. We advise clinicians to screen subjects with BPS/IC for modifiable risk factors for CHD. Neurourol. Urodynam. 33:511-515, 2014.

AB - Aim Vascular factor was proposed as being involved in the etiology of bladder pain syndrome/interstitial cystitis (BPS/IC). However, few studies have attempted to investigate the relationship between BPS/IC and cardiovascular disease. This study aimed to investigate the risk of coronary heart disease (CHD) among BPS/IC subjects during a 3-year follow-up period. Methods Data for this retrospective matched-cohort study were retrieved from the Taiwan "Longitudinal Health Insurance Database 2000." There were 752 BPS/IC female subjects in the study cohort and 3,760 randomly selected female subjects in the comparison cohort. We individually tracked each subject for 3 years and identified each subject that received a subsequent diagnosis of CHD during that follow-up period. Results Results showed that incidence rates of CHD during the 3-year follow-up period were 19.50 (95% confidence interval (CI): 14.35-25.95) and 8.87 (95% CI: 7.25-10.74) per 1,000 person-years for the study and comparison cohorts, respectively. The Cox proportional hazards regression suggested that the hazard ratio for CHD in subjects with BPS/IC was 1.65 (95% CI: 1.09-2.48) within the 3-year follow-up period following the index date compared to the comparison subjects after adjusting for monthly income, geographic region, hypertension, diabetes, hyperlipidemia, chronic kidney disease, bladder outlet obstruction, urinary tract infection, chronic pelvic pain, overactive bladder, and number of physician visits during the 3-year follow up period. Conclusions Our study demonstrated an association between BPS/IC and a subsequent CHD diagnosis. We advise clinicians to screen subjects with BPS/IC for modifiable risk factors for CHD. Neurourol. Urodynam. 33:511-515, 2014.

KW - bladder pain syndrome/interstitial cystitis

KW - coronary heart disease

KW - interstitial cystitis

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