Birth seasonality in schizophrenia: Effects of gender and income status

Chin Cheng, El Wui Loh, Ching Heng Lin, Chin Hong Chan, Tsuo Hung Lan

研究成果: 雜誌貢獻文章

10 引文 斯高帕斯(Scopus)

摘要

Aims The aim of this study was to examine the correlations of birth seasonality in schizophrenia, considering influences of gender and income status. Methods The sample consisted of 1 000 000 people in the general population randomly selected from the Taiwan National Health Insurance Research Database. Data for the birth-year period 1950-1989 were extracted for analysis (n = 631 911; 306 194 male, 325 717 female). Subjects with schizophrenia (2796 male, 2251 female) were compared with the general population. Subgroups divided by birth-year periods (10-year interval), gender, and income status (low, medium, high) were analyzed using both the Walter and Elwood seasonality and chi-squared tests. Results The winter/spring birth excess in schizophrenia was 5.3% when compared with the general population. There was a statistically significant excess in winter/spring births than summer/autumn births inschizophrenia patients (relative risk [RR], 1.12; 95% confidence interval [CI]: 1.06-1.18). This winter/spring birth excess in schizophrenia was observed only in female subjects (RR, 1.20; 95%CI: 1.10-1.30), not in male subjects (RR, 1.03; 95%CI: 0.98-1.14), in all subgroups of income status, but was most pronounced in the low income subgroup (RR, 1.20, 1.09, 1.13; 95% CI: 1.05-1.37, 1.01-1.17, 1.02-1.25 for low, medium, and high income status, respectively). Conclusion A gender difference with female predominance of the effect of birth seasonality in schizophrenia, and a more pronounced effect in low income status were noted.
原文英語
頁(從 - 到)426-433
頁數8
期刊Psychiatry and Clinical Neurosciences
67
發行號6
DOIs
出版狀態已發佈 - 九月 1 2013
對外發佈Yes

ASJC Scopus subject areas

  • Neuroscience(all)
  • Neurology
  • Clinical Neurology
  • Psychiatry and Mental health

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