Biomonitoring of blood heavy metals and reproductive hormone level related to low semen quality

Ching Jen Li, Ching Ying Yeh, Ruey Yu Chen, Chii Ruey Tzeng, Bor Cheng Han, Ling Chu Chien

研究成果: 雜誌貢獻文章

6 引文 (Scopus)

摘要

Reproductive hormones and exposure to environmental metals are correlated with low-quality semen. The aim of this study was to evaluate the levels of heavy metals and reproductive hormones in the blood in addition to other relevant factors to clarify the relationship between these factors and semen quality. We recruited 154 male participants from a reproductive medical center. All participants were provided with a questionnaire on lifestyle implementation. The levels of metals in the blood were determined using inductively coupled plasma-mass spectrometry. The levels of hormones in the blood were determined using an automatic gamma counter. Multiple logistic regression analyses were conducted to predict the effects of statistically significant risk factors on semen quality by adjusting for relevant confounders and modifiers. After adjusting for the age, education level, and related factors in the multiple logistic regression analyses, we observed that the increased blood Pb levels were significantly and positively associated with low semen quality. High blood Pb levels (>50. μg/L) had an 11-fold risk of low semen quality. Our results suggest that progressive motility sperm may be a sensitive indicator of the semen quality among all the semen parameters in Taiwan.
原文英語
文章編號17037
頁(從 - 到)815-822
頁數8
期刊Journal of Hazardous Materials
300
DOIs
出版狀態已發佈 - 十二月 30 2015

指紋

Semen Analysis
Environmental Monitoring
Hormones
biomonitoring
Heavy Metals
Heavy metals
hormone
Blood
blood
heavy metal
Logistics
logistics
Metals
Inductively coupled plasma mass spectrometry
Logistic Models
Regression Analysis
metal
motility
risk factor
lifestyle

ASJC Scopus subject areas

  • Health, Toxicology and Mutagenesis
  • Pollution
  • Waste Management and Disposal
  • Environmental Chemistry
  • Environmental Engineering

引用此文

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title = "Biomonitoring of blood heavy metals and reproductive hormone level related to low semen quality",
abstract = "Reproductive hormones and exposure to environmental metals are correlated with low-quality semen. The aim of this study was to evaluate the levels of heavy metals and reproductive hormones in the blood in addition to other relevant factors to clarify the relationship between these factors and semen quality. We recruited 154 male participants from a reproductive medical center. All participants were provided with a questionnaire on lifestyle implementation. The levels of metals in the blood were determined using inductively coupled plasma-mass spectrometry. The levels of hormones in the blood were determined using an automatic gamma counter. Multiple logistic regression analyses were conducted to predict the effects of statistically significant risk factors on semen quality by adjusting for relevant confounders and modifiers. After adjusting for the age, education level, and related factors in the multiple logistic regression analyses, we observed that the increased blood Pb levels were significantly and positively associated with low semen quality. High blood Pb levels (>50. μg/L) had an 11-fold risk of low semen quality. Our results suggest that progressive motility sperm may be a sensitive indicator of the semen quality among all the semen parameters in Taiwan.",
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author = "Li, {Ching Jen} and Yeh, {Ching Ying} and Chen, {Ruey Yu} and Tzeng, {Chii Ruey} and Han, {Bor Cheng} and Chien, {Ling Chu}",
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AU - Li, Ching Jen

AU - Yeh, Ching Ying

AU - Chen, Ruey Yu

AU - Tzeng, Chii Ruey

AU - Han, Bor Cheng

AU - Chien, Ling Chu

PY - 2015/12/30

Y1 - 2015/12/30

N2 - Reproductive hormones and exposure to environmental metals are correlated with low-quality semen. The aim of this study was to evaluate the levels of heavy metals and reproductive hormones in the blood in addition to other relevant factors to clarify the relationship between these factors and semen quality. We recruited 154 male participants from a reproductive medical center. All participants were provided with a questionnaire on lifestyle implementation. The levels of metals in the blood were determined using inductively coupled plasma-mass spectrometry. The levels of hormones in the blood were determined using an automatic gamma counter. Multiple logistic regression analyses were conducted to predict the effects of statistically significant risk factors on semen quality by adjusting for relevant confounders and modifiers. After adjusting for the age, education level, and related factors in the multiple logistic regression analyses, we observed that the increased blood Pb levels were significantly and positively associated with low semen quality. High blood Pb levels (>50. μg/L) had an 11-fold risk of low semen quality. Our results suggest that progressive motility sperm may be a sensitive indicator of the semen quality among all the semen parameters in Taiwan.

AB - Reproductive hormones and exposure to environmental metals are correlated with low-quality semen. The aim of this study was to evaluate the levels of heavy metals and reproductive hormones in the blood in addition to other relevant factors to clarify the relationship between these factors and semen quality. We recruited 154 male participants from a reproductive medical center. All participants were provided with a questionnaire on lifestyle implementation. The levels of metals in the blood were determined using inductively coupled plasma-mass spectrometry. The levels of hormones in the blood were determined using an automatic gamma counter. Multiple logistic regression analyses were conducted to predict the effects of statistically significant risk factors on semen quality by adjusting for relevant confounders and modifiers. After adjusting for the age, education level, and related factors in the multiple logistic regression analyses, we observed that the increased blood Pb levels were significantly and positively associated with low semen quality. High blood Pb levels (>50. μg/L) had an 11-fold risk of low semen quality. Our results suggest that progressive motility sperm may be a sensitive indicator of the semen quality among all the semen parameters in Taiwan.

KW - Lead (Pb)

KW - Low semen quality

KW - Reproductive hormones

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