Autophagy facilitates an IFN-γ response and signal transduction

Yu-Ping Chang, Chia-Ling Chen, Su-O. Chen, Yee-Shin Lin, Cheng-Chieh Tsai, Wei-Ching Huang, Chi-Yun Wang, Chia-Yuan Hsieh, Pui-Ching Choi, Chiou Feng Lin

研究成果: 雜誌貢獻文章同行評審

11 引文 斯高帕斯(Scopus)

摘要

Autophagy, that is directly triggered by invaded pathogens and indirectly triggered by IFN-γ, acts as a defense by mediating intracellular microbial recognition and clearance. In addition, autophagy contributes to inflammation by facilitating an IFN-γ response and signal transduction. For immune escape, downregulated autophagy may be a strategy used by microbes.
原文英語
頁(從 - 到)888-894
頁數7
期刊Microbes and Infection
13
發行號11
DOIs
出版狀態已發佈 - 十月 2011

ASJC Scopus subject areas

  • 微生物學
  • 免疫學
  • 傳染性疾病

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