Automatic spot detection of CDNA microarray images using mathematical morphology methods

Chiao Ling Shih, Hung Wen Chiu

研究成果: 書貢獻/報告類型會議貢獻

3 引文 斯高帕斯(Scopus)

摘要

cDNA microarray is widely used to identify and quantify different gene-expression for large-scale analysis. In order to extract microarray data precisely from microarray images, robust image processing is indispensable. Most microarray image processing methods are still semiautomatic because of the variations between different arrayers and spots properties. This study attempts to propose an automatic spot detection algorithm using mathematical morphology methods. Watershed transform is the main technique for our spot automatic detection method. To avoid the over-segment problem brought on the sensitive to noises of gradient image used m watershed algorithm, we preprocessed the image using morphological opening operator. Internal and external marker for allocating watershed immersion positions were used to reduce the number of image segments. The result showed that our morphological methods achieved automatic spot detection on non-supervised environment.
原文英語
主出版物標題APBME 2003 - IEEE EMBS Asian-Pacific Conference on Biomedical Engineering 2003
發行者Institute of Electrical and Electronics Engineers Inc.
頁面70-71
頁數2
ISBN(列印)0780379438, 9780780379435
DOIs
出版狀態已發佈 - 2003
事件IEEE EMBS Asian-Pacific Conference on Biomedical Engineering 2003, APBME 2003 - Kyoto-Osaka-Nara, 日本
持續時間: 十月 20 2003十月 22 2003

其他

其他IEEE EMBS Asian-Pacific Conference on Biomedical Engineering 2003, APBME 2003
國家日本
城市Kyoto-Osaka-Nara
期間10/20/0310/22/03

ASJC Scopus subject areas

  • Biomedical Engineering

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