Atomic layer deposition of titanium dioxide on cellulose acetate for enhanced hemostasis

G. Kevin Hyde, S. Michael Stewart, Giovanna Scarel, Gregory N. Parsons, Chun Che Shih, Chun Ming Shih, Shing Jong Lin, Yea Yang Su, Nancy A. Monteiro-Riviere, Roger J. Narayan

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22 引文 斯高帕斯(Scopus)


TiO2 films may be used to alter the wettability and hemocompatibility of cellulose materials. In this study, pure and stoichiometric TiO2 films were grown using atomic layer deposition on both silicon and cellulose substrates. The films were grown with uniform thicknesses and with a growth rate in agreement with literature results. The TiO2 films were shown to profoundly alter the water contact angle values of cellulose in a manner dependent upon processing characteristics. Higher amounts of protein adsorption indicated by blurry areas on images generated by scanning electron microscopy were noted on TiO2-coated cellulose acetate than on uncoated cellulose acetate. These results suggest that atomic layer deposition is an appropriate method for improving the biological properties of hemostatic agents and other blood-contacting biomaterials.
頁(從 - 到)213-223
期刊Biotechnology Journal
出版狀態已發佈 - 二月 2011

ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology
  • Molecular Medicine

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