Associations between particulate sulfate and organic carbon exposures and heart rate variability in patients with or at risk for cardiovascular diseases

Kai Jen Chuang, Chang Chuan Chan, Ta Chen Su, Lian Yu Lin, Chung Te Lee

研究成果: 雜誌貢獻文章

40 引文 斯高帕斯(Scopus)

摘要

OBJECTIVE: It is still unknown whether specific components in fine particles are associated with heart rate variability (HRV) reduction. METHODS: We recruited 46 patients with or at risk for cardiovascular diseases to measure 24-hour HRV by ambulatory electrocardiographic monitoring. Fixed-site air-monitoring stations were used to represent participants' exposures to particles with aerodynamic diameters less than 10 μm (PM10) and 2.5 μm (PM2.5), and particulate components of sulfate, nitrate, organic carbon (OC) and elemental carbon, and gaseous pollutants. RESULTS: We found that HRV reduction was associated with sulfate, OC, and PM2.5 but not with the other five pollutants in single-pollutant models. Sulfate was found to remain in significant association with HRV reduction adjusting for OC and PM2.5 in three-pollutant models. CONCLUSIONS: Exposures to sulfate and OC in PM2.5 were associated with HRV reduction in patients with or at risk for cardiovascular diseases.

原文英語
頁(從 - 到)610-617
頁數8
期刊Journal of Occupational and Environmental Medicine
49
發行號6
DOIs
出版狀態已發佈 - 六月 2007
對外發佈Yes

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

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