Association of nucleophosmin/B23 with bladder cancer recurrence based on immunohistochemical assessment in clinical samples

Ke Hung Tsui, Horng Heng Juang, Tsong Hai Lee, Phei Lang Chang, Chien Lun Chen, Benjamin Yat Ming Yung

研究成果: 雜誌貢獻文章同行評審

30 引文 斯高帕斯(Scopus)

摘要

Aim: To investigate the possible correlation of nucleophosmin/B23 expression with bladder carcinoma recurrence. Methods: Surgically-resected bladder tumors staged pTa to pT4 were examined for nucleophosmin/B23 expression by immuno-histochemistry. The study group consisted of 132 consecutive patients surgically treated at Chang Gung Memorial Hospital between December 1998 and November 1999. The mean follow up was 72 months (range: 48-84 months). Results: Nuclear nucleophosmin/B23 staining was detected in 96% of advanced stage and poorly-differentiated tumors. Higher nucleophosmin/B23 levels were linked to more advanced tumor stages, grades, poor prognosis, and likelihood of recurrence (P
原文英語
頁(從 - 到)364-370
頁數7
期刊Acta Pharmacologica Sinica
29
發行號3
DOIs
出版狀態已發佈 - 3月 2008
對外發佈

ASJC Scopus subject areas

  • 藥理
  • 藥學(醫學)

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