Association of long-term indoor exposure to fine particles with pulmonary effects in Northern Taiwan

Li Te Chang, I. Jung Liu, Ta Yuan Chang, Gui Bing Hong, Lian Yu Lin, Hsiao Chi Chuang, Kin Fai Ho, Kai Jen Chuang

研究成果: 雜誌貢獻文章同行評審

摘要

An association between short-term indoor exposure to fine particles (PM2.5) and acute respiratory effects has been reported. It is still unclear whether long-term indoor exposure to PM2.5 is associated with pulmonary events. This study recruited 1023 healthy adult homeworkers to conduct a prospective observational study from 2010 to 2021. Four repeated home visits per year were conducted for each participant to measure 24-hour PM2.5 and peak expiratory flow rate (PEFR) and to collect blood samples for absolute eosinophil count (AEC) and carcinoembryonic antigen (CEA) analysis. Additionally, a questionnaire related to personal characteristics, health status and home characteristics was conducted for each participant. The mixed-effects models showed a significant association of PM2.5 with increased CEA and AEC and decreased % predicted PEFR. No significant association between low-level PM2.5 exposure (10-year mean level < 10 μg/m3) and adverse pulmonary effects was observed. The present study concluded that long-term indoor exposure to PM2.5 at a concentration higher than 10 μg/m3 was associated with adverse pulmonary effects among healthy adult homeworkers.
原文英語
文章編號153097
期刊Science of the Total Environment
821
DOIs
出版狀態已發佈 - 5月 15 2022

ASJC Scopus subject areas

  • 環境工程
  • 環境化學
  • 廢物管理和處置
  • 污染

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