Association between Testicular Cancer and Epididymoorchitis: A Population-Based Case-Control Study

Li Ting Kao, Herng Ching Lin, Shiu Dong Chung, Chao Yuan Huang

研究成果: 雜誌貢獻文章同行評審

10 引文 斯高帕斯(Scopus)


Even though epididymoorchitis and testicular cancer (TC) may have similar pathophysiological pathways, no prior study has attempted to determine the association between these two diseases. This case-control study investigated the relationship between TC and prior epididymoorchitis by using a large population-based database. We used the Taiwan Longitudinal Health Insurance Database 2005 to select 372 patients who had received a diagnosis of TC and 3,720 age-matched controls without TC. We found that of the total sample of 4,092 patients, 53 (1.3%) had received a diagnosis of epididymoorchitis prior to the index date. Patients with TC had a higher prevalence of prior epididymoorchitis than that of patients without TC (11.0% vs. 0.3%, p <0.001). Conditional logistic regression showed that prior epididymoorchitis was significantly associated with TC (crude OR = 38.24, 95% CI = 19.91-73.46). The association remained statistically significant even after adjustment for the other variables (OR = 47.17, 95% CI = 23.83-93.40). This study showed that patients with TC have higher odds of prior epididymoorchitis than do those without TC even after adjustment for potential confounders.
期刊Scientific Reports
出版狀態已發佈 - 3月 15 2016

ASJC Scopus subject areas

  • 多學科


深入研究「Association between Testicular Cancer and Epididymoorchitis: A Population-Based Case-Control Study」主題。共同形成了獨特的指紋。