Association between ingested arsenic and cataracts

Lai Chu See, Jiahn Shing Lee, Yu Mei Hsueh, Ming Chang Tu, Chien Jen Chen

研究成果: 書貢獻/報告類型章節

1 引文 斯高帕斯(Scopus)

摘要

An eye examination was added in the 1996 followup of the blackfoot-disease-endemic cohort of southwestern Taiwan to study whether long-term exposure to inorganic arsenic has any effect on various types of cataracts. The Lens Opacities System III was used to classify different types of cataracts. Cumulative arsenic exposure was derived from the history of consuming artesian well water from the 1988 baseline interview, and the arsenic level of the well water from two government surveys. A total of 349 participants were involved in the study. Posterior subcapsular (PSC) opacities were seen in 22% of the study subjects, higher than in most previous reports. Cumulative arsenic exposure had a dose–response relationship with prevalence of PSC (p = 0.014), after adjustment for age, sex, DM status and sunlight exposure. A large study is needed to confirm the present finding, or an animal study will be helpful in elucidating the mechanism of inorganic arsenic effect on cataracts.

原文英語
主出版物標題Health Hazards of Arsenic Poisoning Environmental
主出版物子標題From Epidemic to Pandemic
發行者World Scientific Publishing Co.
頁面161-178
頁數18
ISBN(電子)9789814291828
ISBN(列印)9814291811, 9789814291811
DOIs
出版狀態已發佈 - 一月 1 2011

ASJC Scopus subject areas

  • 環境科學 (全部)
  • 醫藥 (全部)

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