Association between dietary patterns and serum hepatic enzyme levels in adults with dyslipidemia and impaired fasting plasma glucose

Li Yin Lin, Chien Yeh Hsu, Hung Yi Chiou, Hsiu An Lee, Li Ming Hsu, Po Ya Chang, Adi Lukas Kurniawan, Jane C.J. Chao

研究成果: 雜誌貢獻文章同行評審

摘要

We investigated the association between dietary patterns and serum hepatic enzyme levels in adults with dyslipidemia and impaired fasting glucose in Taiwan. A total of 15,005 subjects (5452 men and 9553 women) aged 35–69 years were selected. Two major dietary patterns were identified by principal component analysis: Western dietary pattern and Mediterranean dietary pattern. Subjects in the highest quartile (Q4) of the Western dietary pattern showed an increased risk of elevated serum alanine aminotransferase (ALT) levels (OR: 1.24, 95% CI: 1.06–1.45, p‐trend = 0.01). Fur‐thermore, in the highest quartile of the Western dietary pattern, subjects with high waist circum‐ference were observed to have a greater risk for developing abnormal serum ALT levels compared to those in the lowest quartile (Q1) (OR: 1.43, 95% CI: 1.04–1.97, p‐trend = 0.01). In the highest quartile of the Western dietary pattern, only women were at an increased risk for having abnormal serum ALT levels (OR: 1.28, 95% CI: 1.04–1.59, p‐trend = 0.03). By contrast, in the highest quartile of the Mediterranean dietary pattern, only men were at a reduced risk for having abnormal serum gamma‐glutamyl transferase (GGT) levels (OR: 0.72, 95% CI: 0.53–0.97, p‐trend = 0.048). We report a positive association between the Western dietary pattern and abnormal serum ALT levels.

原文英語
文章編號987
頁(從 - 到)1-17
頁數17
期刊Nutrients
13
發行號3
DOIs
出版狀態已發佈 - 三月 2021

ASJC Scopus subject areas

  • Food Science
  • Nutrition and Dietetics

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