Association between chronic hepatitis C virus infection and bone mineral density

Jung-Chun Lin, Tsai-Yuan Hsieh, Chia-Chun Wu, Peng-Jen Chen, Tung-Hung Chueh, Wei-Kuo Chang, Heng-Cheng Chu

研究成果: 雜誌貢獻文章

23 引文 斯高帕斯(Scopus)

摘要

Whether chronic hepatitis C virus (HCV) infection is a risk factor for the development of bone disease has long been controversial. For this reason, chronic HCV-infected participants (n = 69) were recruited into a prospective cohort study and underwent dual-energy X-ray absorptiometry for determination of bone mineral density (BMD). Fibrosis staging was evaluated according to the noninvasive index FIB-4. T scores at the femoral neck and lumbar spine were used as the primary outcome variables to assess the association between degree of liver disease and BMD. The study cohort was 41 % male with a mean age of 53.6 years. The mean BMD, Z score, and T score values of lumbar spine in chronic hepatitis C (CHC) patients were significantly lower than those in healthy controls (p
原文英語
頁(從 - 到)423-429
頁數7
期刊Calcified Tissue International
91
發行號6
DOIs
出版狀態已發佈 - 2012
對外發佈Yes

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    Lin, J-C., Hsieh, T-Y., Wu, C-C., Chen, P-J., Chueh, T-H., Chang, W-K., & Chu, H-C. (2012). Association between chronic hepatitis C virus infection and bone mineral density. Calcified Tissue International, 91(6), 423-429. https://doi.org/10.1007/s00223-012-9653-y