Association between apolipoprotein E genotype and outcome of traumatic brain injury

Ming F. Chiang, J. G. Chang, C. J. Hu, L. Dunn, J. A R Nicoll

研究成果: 雜誌貢獻文章

77 引文 斯高帕斯(Scopus)

摘要

Background. The prognosis of traumatic brain injury is quite variable and not fully explained by the known factors. This study is to examine if the polymorphism of apolipoprotein E (apoE) influences the outcome of traumatic brain injury. Methods. Over a period of twelve months, we prospectively studied 100 patients who sustained traumatic brain injuries and were admitted to our neurosurgical unit. Findings. Nineteen patients were apoE4(+) and 81 patients were apoE4(-). There was no significant difference between apoE4(+) and apoE4(-) groups in the cause of injury (p = 0.288), type of brain injury (p = 0.983) and choice of treatment (p = 0.88). The proportion of patients with a lower GCS (

原文英語
頁(從 - 到)649-654
頁數6
期刊Acta Neurochirurgica
145
發行號8
DOIs
出版狀態已發佈 - 八月 1 2003
對外發佈Yes

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

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